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A New PqsR Inverse Agonist Potentiates Tobramycin Efficacy to Eradicate Pseudomonas aeruginosa Biofilms.
Schütz, Christian; Ho, Duy-Khiet; Hamed, Mostafa Mohamed; Abdelsamie, Ahmed Saad; Röhrig, Teresa; Herr, Christian; Kany, Andreas Martin; Rox, Katharina; Schmelz, Stefan; Siebenbürger, Lorenz; Wirth, Marius; Börger, Carsten; Yahiaoui, Samir; Bals, Robert; Scrima, Andrea; Blankenfeldt, Wulf; Horstmann, Justus Constantin; Christmann, Rebekka; Murgia, Xabier; Koch, Marcus; Berwanger, Aylin; Loretz, Brigitta; Hirsch, Anna Katharina Herta; Hartmann, Rolf Wolfgang; Lehr, Claus-Michael; Empting, Martin.
Afiliação
  • Schütz C; Helmholtz-Institute for Pharmaceutical Research Saarland (HIPS)-Helmholtz Centre for Infection Research (HZI), Campus E8.1, Saarbrücken, 66123, Germany.
  • Ho DK; German Centre for Infection Research (DZIF), Partner Site Hannover-Braunschweig, Saarbrücken, 66123, Germany.
  • Hamed MM; Department of Pharmacy, Saarland University, Campus E8.1, Saarbrücken, 66123, Germany.
  • Abdelsamie AS; Helmholtz-Institute for Pharmaceutical Research Saarland (HIPS)-Helmholtz Centre for Infection Research (HZI), Campus E8.1, Saarbrücken, 66123, Germany.
  • Röhrig T; Department of Pharmacy, Saarland University, Campus E8.1, Saarbrücken, 66123, Germany.
  • Herr C; Department of Bioengineering, School of Medicine, University of Washington, Seattle, WA, 98195, USA.
  • Kany AM; Helmholtz-Institute for Pharmaceutical Research Saarland (HIPS)-Helmholtz Centre for Infection Research (HZI), Campus E8.1, Saarbrücken, 66123, Germany.
  • Rox K; German Centre for Infection Research (DZIF), Partner Site Hannover-Braunschweig, Saarbrücken, 66123, Germany.
  • Schmelz S; Helmholtz-Institute for Pharmaceutical Research Saarland (HIPS)-Helmholtz Centre for Infection Research (HZI), Campus E8.1, Saarbrücken, 66123, Germany.
  • Siebenbürger L; German Centre for Infection Research (DZIF), Partner Site Hannover-Braunschweig, Saarbrücken, 66123, Germany.
  • Wirth M; Chemistry of Natural and Microbial Products Department, National Research Centre, Dokki, Cairo, 12622, Egypt.
  • Börger C; Helmholtz-Institute for Pharmaceutical Research Saarland (HIPS)-Helmholtz Centre for Infection Research (HZI), Campus E8.1, Saarbrücken, 66123, Germany.
  • Yahiaoui S; German Centre for Infection Research (DZIF), Partner Site Hannover-Braunschweig, Saarbrücken, 66123, Germany.
  • Bals R; Department of Internal Medicine V - Pulmonology, Allergology and Critical Care Medicine, Saarland University, Building 41, Homburg, 66421, Germany.
  • Scrima A; Helmholtz-Institute for Pharmaceutical Research Saarland (HIPS)-Helmholtz Centre for Infection Research (HZI), Campus E8.1, Saarbrücken, 66123, Germany.
  • Blankenfeldt W; German Centre for Infection Research (DZIF), Partner Site Hannover-Braunschweig, Saarbrücken, 66123, Germany.
  • Horstmann JC; German Centre for Infection Research (DZIF), Partner Site Hannover-Braunschweig, Saarbrücken, 66123, Germany.
  • Christmann R; Department of Chemical Biology (CBIO), Helmholtz Centre for Infection Research (HZI), Inhoffenstr. 7, Braunschweig, 38124, Germany.
  • Murgia X; German Centre for Infection Research (DZIF), Partner Site Hannover-Braunschweig, Saarbrücken, 66123, Germany.
  • Koch M; Department of Structure and Function of Proteins (SFPR), Helmholtz Centre for Infection Research (HZI), Inhoffenstr. 7, Braunschweig, 38124, Germany.
  • Berwanger A; PharmBioTec GmbH, Science Park 1, Saarbrücken, 66123, Germany.
  • Loretz B; PharmBioTec GmbH, Science Park 1, Saarbrücken, 66123, Germany.
  • Hirsch AKH; PharmBioTec GmbH, Science Park 1, Saarbrücken, 66123, Germany.
  • Hartmann RW; Helmholtz-Institute for Pharmaceutical Research Saarland (HIPS)-Helmholtz Centre for Infection Research (HZI), Campus E8.1, Saarbrücken, 66123, Germany.
  • Lehr CM; German Centre for Infection Research (DZIF), Partner Site Hannover-Braunschweig, Saarbrücken, 66123, Germany.
  • Empting M; Department of Internal Medicine V - Pulmonology, Allergology and Critical Care Medicine, Saarland University, Building 41, Homburg, 66421, Germany.
Adv Sci (Weinh) ; 8(12): e2004369, 2021 06.
Article em En | MEDLINE | ID: mdl-34165899
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pseudomonas aeruginosa / Infecções por Pseudomonas / Tobramicina / Quinolonas / Biofilmes / Percepção de Quorum Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Adv Sci (Weinh) Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Alemanha
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pseudomonas aeruginosa / Infecções por Pseudomonas / Tobramicina / Quinolonas / Biofilmes / Percepção de Quorum Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Adv Sci (Weinh) Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Alemanha