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Combined computational and cellular screening identifies synergistic inhibition of SARS-CoV-2 by lenvatinib and remdesivir.
Pohl, Marie O; Busnadiego, Idoia; Marrafino, Francesco; Wiedmer, Lars; Hunziker, Annika; Fernbach, Sonja; Glas, Irina; Moroz-Omori, Elena V; Hale, Benjamin G; Caflisch, Amedeo; Stertz, Silke.
Afiliação
  • Pohl MO; Institute of Medical Virology, University of Zurich, Winterthurerstrasse 190, 8057 Zurich, Switzerland.
  • Busnadiego I; Institute of Medical Virology, University of Zurich, Winterthurerstrasse 190, 8057 Zurich, Switzerland.
  • Marrafino F; Department of Biochemistry, University of Zurich, Winterthurerstrasse 190, 8057 Zurich, Switzerland.
  • Wiedmer L; Department of Pharmacy, University of Salerno, Fisciano SA, 84084, Italy.
  • Hunziker A; Department of Biochemistry, University of Zurich, Winterthurerstrasse 190, 8057 Zurich, Switzerland.
  • Fernbach S; Institute of Medical Virology, University of Zurich, Winterthurerstrasse 190, 8057 Zurich, Switzerland.
  • Glas I; Institute of Medical Virology, University of Zurich, Winterthurerstrasse 190, 8057 Zurich, Switzerland.
  • Moroz-Omori EV; Institute of Medical Virology, University of Zurich, Winterthurerstrasse 190, 8057 Zurich, Switzerland.
  • Hale BG; Department of Biochemistry, University of Zurich, Winterthurerstrasse 190, 8057 Zurich, Switzerland.
  • Caflisch A; Institute of Medical Virology, University of Zurich, Winterthurerstrasse 190, 8057 Zurich, Switzerland.
  • Stertz S; Department of Biochemistry, University of Zurich, Winterthurerstrasse 190, 8057 Zurich, Switzerland.
J Gen Virol ; 102(7)2021 07.
Article em En | MEDLINE | ID: mdl-34319869
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Compostos de Fenilureia / Quinolinas / Monofosfato de Adenosina / Alanina / Quimases / SARS-CoV-2 / COVID-19 / Tratamento Farmacológico da COVID-19 Tipo de estudo: Diagnostic_studies / Screening_studies Limite: Animals / Humans Idioma: En Revista: J Gen Virol Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Suíça
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Compostos de Fenilureia / Quinolinas / Monofosfato de Adenosina / Alanina / Quimases / SARS-CoV-2 / COVID-19 / Tratamento Farmacológico da COVID-19 Tipo de estudo: Diagnostic_studies / Screening_studies Limite: Animals / Humans Idioma: En Revista: J Gen Virol Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Suíça