Protective effects of perindopril against indomethacin-induced gastric mucosal damage through modulation of DDAH-1/ADMA and ACE-2/ANG-(1-7) signaling pathways.

Mohamed, Yasmin T; Naguib, Ibrahim A; Abo-Saif, Ali A; Mohamed, Wafaa R

Mohamed, Yasmin T; Naguib, Ibrahim A; Abo-Saif, Ali A; Mohamed, Wafaa R.

Afiliação

Mohamed YT; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Nahda University, Beni-Suef, Egypt.
Naguib IA; Department of Pharmaceutical Chemistry, College of Pharmacy, Taif University, Taif, Saudi Arabia.
Abo-Saif AA; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Nahda University, Beni-Suef, Egypt.
Mohamed WR; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Beni-Suef University, Beni-Suef, Egypt.

Drug Chem Toxicol ; 45(6): 2509-2518, 2022 Nov.

Article em En | MEDLINE | ID: mdl-34384315

Assuntos

Indometacina; Perindopril; Ratos; Animais; Indometacina/toxicidade; Perindopril/farmacologia; Fator de Necrose Tumoral alfa/metabolismo; Pantoprazol; Ciclo-Oxigenase 2; Transdução de Sinais; Anti-Inflamatórios não Esteroides; Superóxido Dismutase/metabolismo; Biomarcadores; Prostaglandinas E

Palavras-chave

ACE-2; ADMA; Perindopril; gastric ulcer; indomethacin; oxidative stress

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Indometacina / Perindopril Limite: Animals Idioma: En Revista: Drug Chem Toxicol Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Egito

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