Effects of HMGB1 on Tricellular Tight Junctions via TGF-ß Signaling in Human Nasal Epithelial Cells.

Ohwada, Kizuku; Konno, Takumi; Kohno, Takayuki; Nakano, Masaya; Ohkuni, Tsuyoshi; Miyata, Ryo; Kakuki, Takuya; Kondoh, Masuo; Takano, Kenichi; Kojima, Takashi

Ohwada, Kizuku; Konno, Takumi; Kohno, Takayuki; Nakano, Masaya; Ohkuni, Tsuyoshi; Miyata, Ryo; Kakuki, Takuya; Kondoh, Masuo; Takano, Kenichi; Kojima, Takashi.

Afiliação

Ohwada K; Department of Cell Science, Research Institute for Frontier Medicine, Sapporo Medical University School of Medicine, Sapporo 060-8556, Japan.
Konno T; Department of Otolaryngology, Sapporo Medical University School of Medicine, Sapporo 060-8556, Japan.
Kohno T; Department of Cell Science, Research Institute for Frontier Medicine, Sapporo Medical University School of Medicine, Sapporo 060-8556, Japan.
Nakano M; Department of Cell Science, Research Institute for Frontier Medicine, Sapporo Medical University School of Medicine, Sapporo 060-8556, Japan.
Ohkuni T; Department of Cell Science, Research Institute for Frontier Medicine, Sapporo Medical University School of Medicine, Sapporo 060-8556, Japan.
Miyata R; Department of Otolaryngology, Sapporo Medical University School of Medicine, Sapporo 060-8556, Japan.
Kakuki T; Department of Otolaryngology, Sapporo Medical University School of Medicine, Sapporo 060-8556, Japan.
Kondoh M; Department of Otolaryngology, Sapporo Medical University School of Medicine, Sapporo 060-8556, Japan.
Takano K; Department of Otolaryngology, Sapporo Medical University School of Medicine, Sapporo 060-8556, Japan.
Kojima T; Drug Discovery Center, Graduate School of Pharmaceutical Sciences, Osaka University, Suita 565-0871, Japan.

Int J Mol Sci ; 22(16)2021 Aug 04.

Article em En | MEDLINE | ID: mdl-34445093

Assuntos

Proteína HMGB1/metabolismo; Mucosa Nasal/metabolismo; Transdução de Sinais; Junções Íntimas/metabolismo; Fator de Crescimento Transformador beta/metabolismo; Células Cultivadas; Células Epiteliais/citologia; Células Epiteliais/metabolismo; Humanos; Mucosa Nasal/citologia

Palavras-chave

2.5D matrigel culture; HMGB1; OSM; TGF-ß type I receptor inhibitor; angulin-1/LSR; hTERT; human nasal epithelial cells; p63; tight junctions

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Transdução de Sinais / Fator de Crescimento Transformador beta / Junções Íntimas / Proteína HMGB1 / Mucosa Nasal Limite: Humans Idioma: En Revista: Int J Mol Sci Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Japão

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