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Exosomal tau with seeding activity is released from Alzheimer's disease synapses, and seeding potential is associated with amyloid beta.
Miyoshi, Emily; Bilousova, Tina; Melnik, Mikhail; Fakhrutdinov, Danyl; Poon, Wayne W; Vinters, Harry V; Miller, Carol A; Corrada, Maria; Kawas, Claudia; Bohannan, Ryan; Caraway, Chad; Elias, Chris; Maina, Katherine N; Campagna, Jesus J; John, Varghese; Gylys, Karen Hoppens.
Afiliação
  • Miyoshi E; UCLA School of Nursing, UCLA School of Medicine, Los Angeles, CA, USA.
  • Bilousova T; UCLA School of Nursing, UCLA School of Medicine, Los Angeles, CA, USA.
  • Melnik M; Mary S. Easton Center for Alzheimer's Research at UCLA, UCLA School of Medicine, Los Angeles, CA, USA.
  • Fakhrutdinov D; Department of Neurology, UCLA School of Medicine, Los Angeles, CA, USA.
  • Poon WW; UCLA School of Nursing, UCLA School of Medicine, Los Angeles, CA, USA.
  • Vinters HV; Neuroscience Interdepartmental Program, UCLA School of Medicine, Los Angeles, CA, USA.
  • Miller CA; UCLA School of Nursing, UCLA School of Medicine, Los Angeles, CA, USA.
  • Corrada M; Institute for Memory Impairments and Neurological Disorders, UC Irvine, Irvine, CA, USA.
  • Kawas C; Mary S. Easton Center for Alzheimer's Research at UCLA, UCLA School of Medicine, Los Angeles, CA, USA.
  • Bohannan R; Department of Neurology, UCLA School of Medicine, Los Angeles, CA, USA.
  • Caraway C; Department of Pathology and Laboratory Medicine, UCLA School of Medicine, Los Angeles, CA, USA.
  • Elias C; Department of Pathology, Keck USC School of Medicine, Los Angeles, CA, USA.
  • Maina KN; Department of Neurology, Program in Neuroscience, Keck USC School of Medicine, Los Angeles, CA, USA.
  • Campagna JJ; Institute for Memory Impairments and Neurological Disorders, UC Irvine, Irvine, CA, USA.
  • John V; Department of Neurology, UC Irvine, Irvine, CA, USA.
  • Gylys KH; Institute for Memory Impairments and Neurological Disorders, UC Irvine, Irvine, CA, USA.
Lab Invest ; 101(12): 1605-1617, 2021 12.
Article em En | MEDLINE | ID: mdl-34462532

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Sinapses / Sinaptossomos / Peptídeos beta-Amiloides / Proteínas tau / Doença de Alzheimer Tipo de estudo: Risk_factors_studies Limite: Aged / Aged80 / Animals / Female / Humans / Male / Middle aged Idioma: En Revista: Lab Invest Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Estados Unidos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Sinapses / Sinaptossomos / Peptídeos beta-Amiloides / Proteínas tau / Doença de Alzheimer Tipo de estudo: Risk_factors_studies Limite: Aged / Aged80 / Animals / Female / Humans / Male / Middle aged Idioma: En Revista: Lab Invest Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Estados Unidos