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Structure-Based Optimization of Small Molecule Human Galactokinase Inhibitors.
Liu, Li; Tang, Manshu; Pragani, Rajan; Whitby, Frank G; Zhang, Ya-Qin; Balakrishnan, Bijina; Fang, Yuhong; Karavadhi, Surendra; Tao, Dingyin; LeClair, Christopher A; Hall, Matthew D; Marugan, Juan J; Boxer, Matthew; Shen, Min; Hill, Christopher P; Lai, Kent; Patnaik, Samarjit.
Afiliação
  • Liu L; National Center for Advancing Translational Sciences, National Institutes of Health, 9800 Medical Center Drive, Rockville, Maryland 20850, United States.
  • Tang M; Department of Pediatrics, University of Utah, Salt Lake City, Utah 84108-6500, United States.
  • Pragani R; National Center for Advancing Translational Sciences, National Institutes of Health, 9800 Medical Center Drive, Rockville, Maryland 20850, United States.
  • Whitby FG; Department of Biochemistry, University of Utah School of Medicine, 15 North Medical Drive East, Salt Lake City, Utah 84112, United States.
  • Zhang YQ; National Center for Advancing Translational Sciences, National Institutes of Health, 9800 Medical Center Drive, Rockville, Maryland 20850, United States.
  • Balakrishnan B; Department of Pediatrics, University of Utah, Salt Lake City, Utah 84108-6500, United States.
  • Fang Y; National Center for Advancing Translational Sciences, National Institutes of Health, 9800 Medical Center Drive, Rockville, Maryland 20850, United States.
  • Karavadhi S; National Center for Advancing Translational Sciences, National Institutes of Health, 9800 Medical Center Drive, Rockville, Maryland 20850, United States.
  • Tao D; National Center for Advancing Translational Sciences, National Institutes of Health, 9800 Medical Center Drive, Rockville, Maryland 20850, United States.
  • LeClair CA; National Center for Advancing Translational Sciences, National Institutes of Health, 9800 Medical Center Drive, Rockville, Maryland 20850, United States.
  • Hall MD; National Center for Advancing Translational Sciences, National Institutes of Health, 9800 Medical Center Drive, Rockville, Maryland 20850, United States.
  • Marugan JJ; National Center for Advancing Translational Sciences, National Institutes of Health, 9800 Medical Center Drive, Rockville, Maryland 20850, United States.
  • Boxer M; National Center for Advancing Translational Sciences, National Institutes of Health, 9800 Medical Center Drive, Rockville, Maryland 20850, United States.
  • Shen M; National Center for Advancing Translational Sciences, National Institutes of Health, 9800 Medical Center Drive, Rockville, Maryland 20850, United States.
  • Hill CP; Department of Biochemistry, University of Utah School of Medicine, 15 North Medical Drive East, Salt Lake City, Utah 84112, United States.
  • Lai K; Department of Pediatrics, University of Utah, Salt Lake City, Utah 84108-6500, United States.
  • Patnaik S; National Center for Advancing Translational Sciences, National Institutes of Health, 9800 Medical Center Drive, Rockville, Maryland 20850, United States.
J Med Chem ; 64(18): 13551-13571, 2021 09 23.
Article em En | MEDLINE | ID: mdl-34491744
Assuntos
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pirimidinas / Inibidores Enzimáticos / Galactoquinase Limite: Animals / Female / Humans / Male Idioma: En Revista: J Med Chem Assunto da revista: QUIMICA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pirimidinas / Inibidores Enzimáticos / Galactoquinase Limite: Animals / Female / Humans / Male Idioma: En Revista: J Med Chem Assunto da revista: QUIMICA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Estados Unidos