Evolution of Systemic Therapy in Metastatic Pancreatic Ductal Adenocarcinoma.
Surg Oncol Clin N Am
; 30(4): 673-691, 2021 10.
Article
em En
| MEDLINE
| ID: mdl-34511189
ABSTRACT
Pancreatic ductal adenocarcinoma is characterized by early systemic dissemination, a complex tumor microenvironment, as well as significant intratumoral and intertumoral heterogeneity. Treatment options and survival in pancreatic ductal adenocarcinoma have improved steadily over the last 3 decades. Although cytotoxic chemotherapy is currently the mainstay of treatment for pancreatic ductal adenocarcinoma, evolving therapeutic strategies are aimed at targeting the tumor microenvironment, metabolism, and the tumor-host immune balance.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Neoplasias Pancreáticas
/
Adenocarcinoma
/
Carcinoma Ductal Pancreático
Limite:
Humans
Idioma:
En
Revista:
Surg Oncol Clin N Am
Assunto da revista:
NEOPLASIAS
Ano de publicação:
2021
Tipo de documento:
Article