Shortening of membrane lipid acyl chains compensates for phosphatidylcholine deficiency in choline-auxotroph yeast.

Bao, Xue; Koorengevel, Martijn C; Groot Koerkamp, Marian J A; Homavar, Amir; Weijn, Amrah; Crielaard, Stefan; Renne, Mike F; Lorent, Joseph H; Geerts, Willie Jc; Surma, Michal A; Mari, Muriel; Holstege, Frank C P; Klose, Christian; de Kroon, Anton I P M

Bao, Xue; Koorengevel, Martijn C; Groot Koerkamp, Marian J A; Homavar, Amir; Weijn, Amrah; Crielaard, Stefan; Renne, Mike F; Lorent, Joseph H; Geerts, Willie Jc; Surma, Michal A; Mari, Muriel; Holstege, Frank C P; Klose, Christian; de Kroon, Anton I P M.

Afiliação

Bao X; Membrane Biochemistry & Biophysics, Bijvoet Center for Biomolecular Research and Institute of Biomembranes, Utrecht University, Utrecht, The Netherlands.
Koorengevel MC; Membrane Biochemistry & Biophysics, Bijvoet Center for Biomolecular Research and Institute of Biomembranes, Utrecht University, Utrecht, The Netherlands.
Groot Koerkamp MJA; Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands.
Homavar A; Membrane Biochemistry & Biophysics, Bijvoet Center for Biomolecular Research and Institute of Biomembranes, Utrecht University, Utrecht, The Netherlands.
Weijn A; Membrane Biochemistry & Biophysics, Bijvoet Center for Biomolecular Research and Institute of Biomembranes, Utrecht University, Utrecht, The Netherlands.
Crielaard S; Membrane Biochemistry & Biophysics, Bijvoet Center for Biomolecular Research and Institute of Biomembranes, Utrecht University, Utrecht, The Netherlands.
Renne MF; Membrane Biochemistry & Biophysics, Bijvoet Center for Biomolecular Research and Institute of Biomembranes, Utrecht University, Utrecht, The Netherlands.
Lorent JH; Membrane Biochemistry & Biophysics, Bijvoet Center for Biomolecular Research and Institute of Biomembranes, Utrecht University, Utrecht, The Netherlands.
Geerts WJ; Cryo-Electron Microscopy, Bijvoet Center for Biomolecular Research, Utrecht University, Utrecht, The Netherlands.
Surma MA; Lipotype GmbH, Dresden, Germany.
Mari M; Department of Biomedical Sciences of Cells & Systems, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
Holstege FCP; Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands.
Klose C; Lipotype GmbH, Dresden, Germany.
de Kroon AIPM; Membrane Biochemistry & Biophysics, Bijvoet Center for Biomolecular Research and Institute of Biomembranes, Utrecht University, Utrecht, The Netherlands.

EMBO J ; 40(20): e107966, 2021 10 18.

Article em En | MEDLINE | ID: mdl-34520050

Assuntos

Acetil-CoA Carboxilase/genética; Ácido Graxo Sintases/genética; Bicamadas Lipídicas/metabolismo; Lipídeos de Membrana/metabolismo; Fosfatidilcolinas/deficiência; Saccharomyces cerevisiae/metabolismo; Acetil-CoA Carboxilase/metabolismo; Cromossomos Fúngicos; Ácido Graxo Sintases/metabolismo; Retroalimentação Fisiológica; Regulação Fúngica da Expressão Gênica; Bicamadas Lipídicas/química; Metabolismo dos Lipídeos/genética; Fluidez de Membrana; Lipídeos de Membrana/química; Mutação Puntual; Saccharomyces cerevisiae/genética

Palavras-chave

2n-1 aneuploidy; acetyl-CoA carboxylase; acyl chain length; membrane lipid homeostasis; phosphatidylcholine

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fosfatidilcolinas / Acetil-CoA Carboxilase / Saccharomyces cerevisiae / Ácido Graxo Sintases / Bicamadas Lipídicas / Lipídeos de Membrana Idioma: En Revista: EMBO J Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Holanda

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