Comparative pharmacokinetic study of six lignans in normal and diabetic rats after oral administration of Saururus chinensis extract by LC-MS/MS.

Chen, Hongjiang; Luo, Yiyuan; Liu, Jianan; Chen, Jianwei; Chen, Yong; Li, Xiang

Chen, Hongjiang; Luo, Yiyuan; Liu, Jianan; Chen, Jianwei; Chen, Yong; Li, Xiang.

Afiliação

Chen H; College of Chinese Medicine, Zhejiang Pharmaceutical College, Ningbo, People's Republic of China.
Luo Y; College of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, People's Republic of China.
Liu J; College of Chinese Medicine, Zhejiang Pharmaceutical College, Ningbo, People's Republic of China.
Chen J; College of Chinese Medicine, Zhejiang Pharmaceutical College, Ningbo, People's Republic of China.
Chen Y; College of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, People's Republic of China.
Li X; College of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, People's Republic of China.

Biomed Chromatogr ; 36(2): e5253, 2022 Feb.

Article em En | MEDLINE | ID: mdl-34596250

Assuntos

Diabetes Mellitus Experimental/metabolismo; Lignanas; Extratos Vegetais; Saururaceae/química; Administração Oral; Animais; Cromatografia Líquida de Alta Pressão/métodos; Lignanas/sangue; Lignanas/química; Lignanas/farmacocinética; Masculino; Extratos Vegetais/administração & dosagem; Extratos Vegetais/farmacocinética; Ratos; Ratos Sprague-Dawley; Espectrometria de Massas em Tandem/métodos

Palavras-chave

Saururus chinensis; UHPLC-MS/MS; diabetic rats; ignan; pharmacokinetics

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Extratos Vegetais / Lignanas / Saururaceae / Diabetes Mellitus Experimental Limite: Animals Idioma: En Revista: Biomed Chromatogr Ano de publicação: 2022 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google