Effects of dezocine on morphine tolerance and opioid receptor expression in a rat model of bone cancer pain.

Wu, Lin-Xin; Dong, Yan-Peng; Zhu, Qian-Mei; Zhang, Bo; Ai, Bo-Lun; Yan, Tao; Zhang, Guo-Hua; Sun, Li

Wu, Lin-Xin; Dong, Yan-Peng; Zhu, Qian-Mei; Zhang, Bo; Ai, Bo-Lun; Yan, Tao; Zhang, Guo-Hua; Sun, Li.

Afiliação

Wu LX; Department of Anesthesiology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100021, China.
Dong YP; Department of Anesthesiology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100021, China.
Zhu QM; Department of Anesthesiology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100021, China.
Zhang B; Department of Anesthesiology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100021, China.
Ai BL; Department of Breast Surgical Oncology, National Cancer Center/National Clinical Research Center Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100021, China.
Yan T; Department of Anesthesiology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100021, China. blizzardyt@163.com.
Zhang GH; Department of Anesthesiology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100021, China. d1974@163.com.
Sun L; Department of Anesthesiology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100021, China. ykyzlyysunli@126.com.

BMC Cancer ; 21(1): 1128, 2021 Oct 20.

Article em En | MEDLINE | ID: mdl-34670518

Assuntos

Analgésicos Opioides/farmacologia; Compostos Bicíclicos Heterocíclicos com Pontes/farmacologia; Dor do Câncer/tratamento farmacológico; Tolerância a Medicamentos; Morfina/farmacologia; Receptores Opioides/efeitos dos fármacos; Tetra-Hidronaftalenos/farmacologia; Analgésicos Opioides/administração & dosagem; Animais; Neoplasias Ósseas/complicações; Compostos Bicíclicos Heterocíclicos com Pontes/administração & dosagem; Dor do Câncer/metabolismo; Linhagem Celular Tumoral; Regulação para Baixo/efeitos dos fármacos; Interações Medicamentosas; Quimioterapia Combinada/métodos; Feminino; Temperatura Alta; Hiperalgesia/fisiopatologia; Morfina/administração & dosagem; Medição da Dor/efeitos dos fármacos; Limiar da Dor; Substância Cinzenta Periaquedutal/metabolismo; Ratos; Ratos Wistar; Receptores Opioides/metabolismo; Receptores Opioides delta/metabolismo; Receptores Opioides kappa/efeitos dos fármacos; Receptores Opioides kappa/metabolismo; Receptores Opioides mu/metabolismo; Medula Espinal/metabolismo; Tetra-Hidronaftalenos/administração & dosagem; Regulação para Cima/efeitos dos fármacos

Palavras-chave

Bone cancer pain; Dezocine; Morphine; Opioid receptors; Tolerance

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Tetra-Hidronaftalenos / Receptores Opioides / Compostos Bicíclicos Heterocíclicos com Pontes / Tolerância a Medicamentos / Dor do Câncer / Analgésicos Opioides / Morfina Limite: Animals Idioma: En Revista: BMC Cancer Assunto da revista: NEOPLASIAS Ano de publicação: 2021 Tipo de documento: Article País de afiliação: China

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