microRNAs in female infertility: An overview.
Cell Biochem Funct
; 39(8): 955-969, 2021 Dec.
Article
em En
| MEDLINE
| ID: mdl-34708430
ABSTRACT
Infertility impacts a considerable number of women worldwide, and it affects different aspects of family life and society. Although female infertility is known as a multifactorial disorder, there are strong genetic and epigenetic bases. Studies revealed that miRNAs play critical roles in initiation and development of female infertility related disorders. Early diagnosis and control of these diseases is an essential key for improving disease prognosis and reducing the possibility of infertility and other side effects. Investigating the possible use of miRNAs as biomarkers and therapeutic options is valuable, and it merits attention. Thus, in this article, we reviewed research associated with female diseases and highlighted microRNAs that are related to the polycystic ovary syndrome (up to 30 miRNAs), premature ovarian failure (10 miRNAs), endometriosis (up to 15 miRNAs), uterine fibroids (up to 15 miRNAs), endometrial polyp (3 miRNAs), and pelvic inflammatory (6 miRNAs), which are involved in one or more ovarian or uterine disease-causing processes.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
MicroRNAs
/
Infertilidade Feminina
Tipo de estudo:
Screening_studies
Limite:
Animals
/
Female
/
Humans
Idioma:
En
Revista:
Cell Biochem Funct
Ano de publicação:
2021
Tipo de documento:
Article
País de afiliação:
Irã