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Structural simplification and bioisostere principle lead to Bis-benzodioxole-fibrate derivatives as potential hypolipidemic and hepatoprotective agents.
Xie, Yundong; Liu, Jiping; Shi, Yongheng; Wang, Bin; Wang, Xiaoping; Wang, Wei; Sun, Meng; Xu, Xinya; Cheng, Lifei; He, Shipeng.
Afiliação
  • Xie Y; College of Pharmacy, Shaanxi University of Chinese Medicine, Shiji Ave, Xi'an-xianyang New Ecomic Zone, Shaanxi Province 712046, People's Republic of China.
  • Liu J; College of Pharmacy, Shaanxi University of Chinese Medicine, Shiji Ave, Xi'an-xianyang New Ecomic Zone, Shaanxi Province 712046, People's Republic of China; Key Laboratory of Pharmacodynamics and Material Basis of Chinese Medicine, Shaanxi Administration of Traditional Chinese Medicine, Xianyang 712
  • Shi Y; College of Pharmacy, Shaanxi University of Chinese Medicine, Shiji Ave, Xi'an-xianyang New Ecomic Zone, Shaanxi Province 712046, People's Republic of China; Key Laboratory of Pharmacodynamics and Material Basis of Chinese Medicine, Shaanxi Administration of Traditional Chinese Medicine, Xianyang 712
  • Wang B; College of Pharmacy, Shaanxi University of Chinese Medicine, Shiji Ave, Xi'an-xianyang New Ecomic Zone, Shaanxi Province 712046, People's Republic of China; Key Laboratory of Pharmacodynamics and Material Basis of Chinese Medicine, Shaanxi Administration of Traditional Chinese Medicine, Xianyang 712
  • Wang X; College of Pharmacy, Shaanxi University of Chinese Medicine, Shiji Ave, Xi'an-xianyang New Ecomic Zone, Shaanxi Province 712046, People's Republic of China.
  • Wang W; College of Pharmacy, Shaanxi University of Chinese Medicine, Shiji Ave, Xi'an-xianyang New Ecomic Zone, Shaanxi Province 712046, People's Republic of China.
  • Sun M; College of Pharmacy, Shaanxi University of Chinese Medicine, Shiji Ave, Xi'an-xianyang New Ecomic Zone, Shaanxi Province 712046, People's Republic of China.
  • Xu X; College of Pharmacy, Shaanxi University of Chinese Medicine, Shiji Ave, Xi'an-xianyang New Ecomic Zone, Shaanxi Province 712046, People's Republic of China.
  • Cheng L; Shaanxi Traffic Hospital, 276 Daxue South Road, Beilin District, Xi'an, Shannxi Province 710068, People's Republic of China. Electronic address: 532413532@qq.com.
  • He S; Institute of Translational Medicine, Shanghai University 99 Shangda Road, Shanghai 200444, People's Republic of China. Electronic address: heshipeng@shu.edu.cn.
Bioorg Chem ; 117: 105454, 2021 12.
Article em En | MEDLINE | ID: mdl-34740054
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Substâncias Protetoras / PPAR alfa / Benzodioxóis / Ácidos Fíbricos / Hiperlipidemias / Hipolipemiantes Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Bioorg Chem Ano de publicação: 2021 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Substâncias Protetoras / PPAR alfa / Benzodioxóis / Ácidos Fíbricos / Hiperlipidemias / Hipolipemiantes Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Bioorg Chem Ano de publicação: 2021 Tipo de documento: Article