Synthetic biology: at the crossroads of genetic engineering and human therapeutics-a Keystone Symposia report.
Ann N Y Acad Sci
; 1506(1): 98-117, 2021 12.
Article
em En
| MEDLINE
| ID: mdl-34786712
ABSTRACT
Synthetic biology has the potential to transform cell- and gene-based therapies for a variety of diseases. Sophisticated tools are now available for both eukaryotic and prokaryotic cells to engineer cells to selectively achieve therapeutic effects in response to one or more disease-related signals, thus sparing healthy tissue from potentially cytotoxic effects. This report summarizes the Keystone eSymposium "Synthetic Biology At the Crossroads of Genetic Engineering and Human Therapeutics," which took place on May 3 and 4, 2021. Given that several therapies engineered using synthetic biology have entered clinical trials, there was a clear need for a synthetic biology symposium that emphasizes the therapeutic applications of synthetic biology as opposed to the technical aspects. Presenters discussed the use of synthetic biology to improve T cell, gene, and viral therapies, to engineer probiotics, and to expand upon existing modalities and functions of cell-based therapies.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Terapia Genética
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Engenharia Genética
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Congressos como Assunto
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Biologia Sintética
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Relatório de Pesquisa
Limite:
Animals
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Humans
Idioma:
En
Revista:
Ann N Y Acad Sci
Ano de publicação:
2021
Tipo de documento:
Article