Study on the scanning protocols for measuring bone mineral density by gemstone CT spectral imaging based on European spine phantom.
Acta Radiol
; 64(1): 346-352, 2023 Jan.
Article
em En
| MEDLINE
| ID: mdl-34877886
ABSTRACT
BACKGROUND:
Gemstone spectral computed tomography (GSCT) has been used to measure bone mineral density (BMD) in human vertebrae and animal models gradually.PURPOSE:
To investigate the effect of scanning protocols for BMD measurements by GSCT using the European spine phantom (ESP) and its accuracy and precision. MATERIAL ANDMETHODS:
The ESP number 145 containing three hydroxyapatite (HAP) inserts with densities of 50, 100, and 200â mg/cm3 were labeled as L1, L2, and L3, respectively. Quantitative CT (QCT) protocol and 14 groups of scanning protocols configured by GSCT were used to repeatedly scan the ESP 10 times. Their measurements were compared with the true values of ESP and their relative standard deviation and relative error were calculated.RESULTS:
The measured values of the three inserts at different exposure levels were statistically significant (P < 0.05). The measured values in the 0.8â s/r 260â mA group, 0.5â s/r 630â mA group, and 0.6â s/r 640â mA group were not significantly different from the actual ESP values for L1 and L2. However, the measured values at all the parameters were significantly different from the actual values for the L3.CONCLUSION:
CT gemstone spectral imaging can accurately and quantitatively measure the HAP value of ESP, but the results of BMD will be affected by the scanning protocols. The best scanning parameter of ESP measured by GSCT was 0.8â s/r 260â mA, taking dose into consideration, and the measurement accuracy of vertebrae with low BMD was higher than that of QCT under this parameter.Palavras-chave
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Osteoporose
/
Densidade Óssea
Limite:
Humans
Idioma:
En
Revista:
Acta Radiol
Ano de publicação:
2023
Tipo de documento:
Article