Functional rejuvenation of aged neural stem cells by Plagl2 and anti-Dyrk1a activity.

Kaise, Takashi; Fukui, Masahiro; Sueda, Risa; Piao, Wenhui; Yamada, Mayumi; Kobayashi, Taeko; Imayoshi, Itaru; Kageyama, Ryoichiro

Kaise, Takashi; Fukui, Masahiro; Sueda, Risa; Piao, Wenhui; Yamada, Mayumi; Kobayashi, Taeko; Imayoshi, Itaru; Kageyama, Ryoichiro.

Afiliação

Kaise T; Institute for Frontier Life and Medical Sciences, Kyoto University, Kyoto 606-8507, Japan.
Fukui M; Graduate School of Medicine, Kyoto University, Kyoto 606-8501, Japan.
Sueda R; Institute for Frontier Life and Medical Sciences, Kyoto University, Kyoto 606-8507, Japan.
Piao W; Graduate School of Medicine, Kyoto University, Kyoto 606-8501, Japan.
Yamada M; Institute for Frontier Life and Medical Sciences, Kyoto University, Kyoto 606-8507, Japan.
Kobayashi T; Research Center for Dynamic Living Systems, Graduate School of Biostudies, Kyoto University, Kyoto 606-8501, Japan.
Imayoshi I; Institute for Frontier Life and Medical Sciences, Kyoto University, Kyoto 606-8507, Japan.
Kageyama R; Research Center for Dynamic Living Systems, Graduate School of Biostudies, Kyoto University, Kyoto 606-8501, Japan.

Genes Dev ; 36(1-2): 23-37, 2022 01 01.

Article em En | MEDLINE | ID: mdl-34916302

Assuntos

Células-Tronco Neurais; Rejuvenescimento; Animais; Hipocampo; Camundongos; Neurogênese/genética; Neurônios

Palavras-chave

ATAC-seq; Ascl1; ChIP-seq; Dyrk1a; Plagl2; adult neurogenesis; aged brain; lentivirus; mouse; neural stem cell

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Rejuvenescimento / Células-Tronco Neurais Limite: Animals Idioma: En Revista: Genes Dev Assunto da revista: BIOLOGIA MOLECULAR Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Japão

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