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Functional analysis of the 1p34.3 risk locus implicates GNL2 in high-grade serous ovarian cancer.
Nakamura, Koji; Reid, Brett M; Chen, Ann; Chen, Zhihua; Goode, Ellen L; Permuth, Jennifer B; Teer, Jamie K; Tyrer, Jonathan; Yu, Xiaoqing; Kanetsky, Peter A; Pharoah, Paul D; Gayther, Simon A; Sellers, Thomas A; Lawrenson, Kate; Karreth, Florian A.
Afiliação
  • Nakamura K; Department of Molecular Oncology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL 33612, USA.
  • Reid BM; Department of Cancer Epidemiology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL 33612, USA. Electronic address: brett.reid@moffitt.org.
  • Chen A; Department of Biostatics and Bioinformatics, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL 33612, USA.
  • Chen Z; Department of Biostatics and Bioinformatics, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL 33612, USA.
  • Goode EL; Department of Quantitative Health Sciences, Mayo Clinic, Rochester, MN 55905, USA.
  • Permuth JB; Department of Cancer Epidemiology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL 33612, USA.
  • Teer JK; Department of Biostatics and Bioinformatics, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL 33612, USA.
  • Tyrer J; The Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, CB1 8RN, United Kingdom.
  • Yu X; Department of Biostatics and Bioinformatics, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL 33612, USA.
  • Kanetsky PA; Department of Cancer Epidemiology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL 33612, USA.
  • Pharoah PD; The Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, CB1 8RN, United Kingdom.
  • Gayther SA; Women's Cancer Program at the Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.
  • Sellers TA; TAS Consulting, Portland, OR, USA.
  • Lawrenson K; Women's Cancer Program at the Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.
  • Karreth FA; Department of Molecular Oncology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL 33612, USA. Electronic address: florian.karreth@moffitt.org.
Am J Hum Genet ; 109(1): 116-135, 2022 01 06.
Article em En | MEDLINE | ID: mdl-34965383

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Ovarianas / Cromossomos Humanos Par 1 / Cistadenocarcinoma Seroso / Proteínas de Ligação ao GTP / Predisposição Genética para Doença / Locos de Características Quantitativas Tipo de estudo: Etiology_studies / Prognostic_studies / Risk_factors_studies Limite: Animals / Female / Humans Idioma: En Revista: Am J Hum Genet Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Estados Unidos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Ovarianas / Cromossomos Humanos Par 1 / Cistadenocarcinoma Seroso / Proteínas de Ligação ao GTP / Predisposição Genética para Doença / Locos de Características Quantitativas Tipo de estudo: Etiology_studies / Prognostic_studies / Risk_factors_studies Limite: Animals / Female / Humans Idioma: En Revista: Am J Hum Genet Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Estados Unidos