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Discovery of 2H-chromone-4-one based sulfonamide derivatives as potent retinoic acid receptor-related orphan receptor γt inverse agonists.
Chen, Lei; Su, Mei; Wu, Xian-Zhi; Wang, De-Zhong; Kang, Yang-Yang; Wang, Chun-Gu; Assani, Israa; Wang, Mu-Xuan; Zhao, Shi-Feng; Lv, Shen-Min; Wang, Jia-Wei; Sun, Bo; Li, Yan; Jin, Qiu; Huang, Ri-Zhen; Liao, Zhi-Xin.
Afiliação
  • Chen L; Department of Pharmaceutical Engineering, School of Chemistry and Chemical Engineering and Jiangsu Province Hi-Tech Key Laboratory for Biomedical Research, Southeast University, Nanjing, 211189, China.
  • Su M; Jiangsu Carefree Pharmaceutical Co., Ltd, Nanjing, 210042, China.
  • Wu XZ; Jiangsu Carefree Pharmaceutical Co., Ltd, Nanjing, 210042, China.
  • Wang DZ; Jiangsu Carefree Pharmaceutical Co., Ltd, Nanjing, 210042, China.
  • Kang YY; Jiangsu Carefree Pharmaceutical Co., Ltd, Nanjing, 210042, China.
  • Wang CG; Department of Pharmaceutical Engineering, School of Chemistry and Chemical Engineering and Jiangsu Province Hi-Tech Key Laboratory for Biomedical Research, Southeast University, Nanjing, 211189, China.
  • Assani I; Department of Pharmaceutical Engineering, School of Chemistry and Chemical Engineering and Jiangsu Province Hi-Tech Key Laboratory for Biomedical Research, Southeast University, Nanjing, 211189, China.
  • Wang MX; Department of Pharmaceutical Engineering, School of Chemistry and Chemical Engineering and Jiangsu Province Hi-Tech Key Laboratory for Biomedical Research, Southeast University, Nanjing, 211189, China.
  • Zhao SF; Department of Pharmaceutical Engineering, School of Chemistry and Chemical Engineering and Jiangsu Province Hi-Tech Key Laboratory for Biomedical Research, Southeast University, Nanjing, 211189, China.
  • Lv SM; Department of Pharmaceutical Engineering, School of Chemistry and Chemical Engineering and Jiangsu Province Hi-Tech Key Laboratory for Biomedical Research, Southeast University, Nanjing, 211189, China.
  • Wang JW; Department of Pharmaceutical Engineering, School of Chemistry and Chemical Engineering and Jiangsu Province Hi-Tech Key Laboratory for Biomedical Research, Southeast University, Nanjing, 211189, China.
  • Sun B; Department of Pharmaceutical Engineering, School of Chemistry and Chemical Engineering and Jiangsu Province Hi-Tech Key Laboratory for Biomedical Research, Southeast University, Nanjing, 211189, China.
  • Li Y; Department of Pharmaceutical Engineering, School of Chemistry and Chemical Engineering and Jiangsu Province Hi-Tech Key Laboratory for Biomedical Research, Southeast University, Nanjing, 211189, China.
  • Jin Q; Jiangsu Carefree Pharmaceutical Co., Ltd, Nanjing, 210042, China. Electronic address: jinqiu1982@126.com.
  • Huang RZ; College of Biotechnology, Guilin Medical University, Guilin, 541004, China. Electronic address: rzhuang1783@163.com.
  • Liao ZX; Department of Pharmaceutical Engineering, School of Chemistry and Chemical Engineering and Jiangsu Province Hi-Tech Key Laboratory for Biomedical Research, Southeast University, Nanjing, 211189, China. Electronic address: zxliao@seu.edu.cn.
Eur J Med Chem ; 229: 114065, 2022 Feb 05.
Article em En | MEDLINE | ID: mdl-34971876
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doenças Autoimunes / Sulfonamidas / Cromonas / Receptores do Ácido Retinoico / Inflamação Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans Idioma: En Revista: Eur J Med Chem Ano de publicação: 2022 Tipo de documento: Article País de afiliação: China
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doenças Autoimunes / Sulfonamidas / Cromonas / Receptores do Ácido Retinoico / Inflamação Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans Idioma: En Revista: Eur J Med Chem Ano de publicação: 2022 Tipo de documento: Article País de afiliação: China