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A previously unappreciated polymorphism in the beta chain of I-As expressed in autoimmunity-prone SJL mice: Combined impact on antibody, CD4 T cell recognition and MHC class II dimer structural stability.
Richards, Katherine A; Lavery, Courtney; Keller, Grant L J; Miller, Jim; Baker, Brian M; Sant, Andrea J.
Afiliação
  • Richards KA; David H. Smith Center for Vaccine Biology and Immunology, Department of Microbiology and Immunology, University of Rochester Medical Center, 601 Elmwood Ave, Box 609, Rochester, NY 14642, United States.
  • Lavery C; David H. Smith Center for Vaccine Biology and Immunology, Department of Microbiology and Immunology, University of Rochester Medical Center, 601 Elmwood Ave, Box 609, Rochester, NY 14642, United States.
  • Keller GLJ; Department of Chemistry & Biochemistry and the Harper Cancer Research Institute, University of Notre Dame, 251 Nieuwland Science Hall, Notre Dame, IN 46556, United States.
  • Miller J; David H. Smith Center for Vaccine Biology and Immunology, Department of Microbiology and Immunology, University of Rochester Medical Center, 601 Elmwood Ave, Box 609, Rochester, NY 14642, United States.
  • Baker BM; Department of Chemistry & Biochemistry and the Harper Cancer Research Institute, University of Notre Dame, 251 Nieuwland Science Hall, Notre Dame, IN 46556, United States.
  • Sant AJ; David H. Smith Center for Vaccine Biology and Immunology, Department of Microbiology and Immunology, University of Rochester Medical Center, 601 Elmwood Ave, Box 609, Rochester, NY 14642, United States. Electronic address: andrea_sant@urmc.rochester.edu.
Mol Immunol ; 143: 17-26, 2022 03.
Article em En | MEDLINE | ID: mdl-34995990
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Polimorfismo Genético / Linfócitos T CD4-Positivos / Antígenos de Histocompatibilidade Classe II / Autoimunidade / Multimerização Proteica / Anticorpos Monoclonais Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Mol Immunol Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Polimorfismo Genético / Linfócitos T CD4-Positivos / Antígenos de Histocompatibilidade Classe II / Autoimunidade / Multimerização Proteica / Anticorpos Monoclonais Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Mol Immunol Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Estados Unidos