The historical development and an overview of contemporary keratoprostheses.
Surv Ophthalmol
; 67(4): 1175-1199, 2022.
Article
em En
| MEDLINE
| ID: mdl-35081413
ABSTRACT
Corneal blindness is a major cause of ocular morbidity that affects 4.5 million people worldwide. Though penetrating keratoplasty is an excellent option for most patients with corneal blindness, there are various conditions for which corneal transplantation carries a low likelihood of success. In cases of multiple failed transplants, the keratoprosthesis, an artificial cornea, is a well-documented surgical option, though few models are commercially available. Keratoprostheses also provide a solution to those in developing areas of the world who do not have access to penetrating keratoplasty owing to limitations in the supply of corneal donor tissue. We summarize the history of keratoprostheses, examine the various keratoprosthesis models used across the globe, and highlight efforts to improve the accessibility and biointegration of keratoprosthesis through novel technological developments.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Órgãos Artificiais
/
Doenças da Córnea
Tipo de estudo:
Etiology_studies
/
Observational_studies
/
Prognostic_studies
Limite:
Humans
Idioma:
En
Revista:
Surv Ophthalmol
Ano de publicação:
2022
Tipo de documento:
Article