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Noncoding genetic variation in GATA3 increases acute lymphoblastic leukemia risk through local and global changes in chromatin conformation.
Yang, Hongbo; Zhang, Hui; Luan, Yu; Liu, Tingting; Yang, Wentao; Roberts, Kathryn G; Qian, Mao-Xiang; Zhang, Bo; Yang, Wenjian; Perez-Andreu, Virginia; Xu, Jie; Iyyanki, Sriranga; Kuang, Da; Stasiak, Lena A; Reshmi, Shalini C; Gastier-Foster, Julie; Smith, Colton; Pui, Ching-Hon; Evans, William E; Hunger, Stephen P; Platanias, Leonidas C; Relling, Mary V; Mullighan, Charles G; Loh, Mignon L; Yue, Feng; Yang, Jun J.
Afiliação
  • Yang H; Department of Biochemistry and Molecular Genetics, Feinberg School of Medicine Northwestern University, Chicago, IL, USA.
  • Zhang H; Robert H. Lurie Comprehensive Cancer Center of Northwestern University, Chicago, IL, USA.
  • Luan Y; Obstetrics and Gynecology Hospital, Institute of Reproduction and Development, Fudan University, Shanghai, China.
  • Liu T; Department of Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, TN, USA.
  • Yang W; Department of Hematology/Oncology, Guangzhou Women and Children's Medical Center, Guangzhou, China.
  • Roberts KG; Department of Hematology/Oncology, Shanghai Children's Medical Center, Shanghai, China.
  • Qian MX; Department of Biochemistry and Molecular Genetics, Feinberg School of Medicine Northwestern University, Chicago, IL, USA.
  • Zhang B; Department of Biochemistry and Molecular Genetics, Feinberg School of Medicine Northwestern University, Chicago, IL, USA.
  • Yang W; Department of Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, TN, USA.
  • Perez-Andreu V; Department of Pathology, St. Jude Children's Research Hospital, Memphis, TN, USA.
  • Xu J; Department of Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, TN, USA.
  • Iyyanki S; Bioinformatics and Genomics Program, The Pennsylvania State University, University Park, PA, USA.
  • Kuang D; Department of Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, TN, USA.
  • Stasiak LA; Department of Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, TN, USA.
  • Reshmi SC; Internal Medicine Department, MountainView Hospital, University of Reno, Las Vegas, NV, USA.
  • Gastier-Foster J; Department of Biochemistry and Molecular Biology, Penn State School of Medicine, Hershey, PA, USA.
  • Smith C; Department of Biochemistry and Molecular Biology, Penn State School of Medicine, Hershey, PA, USA.
  • Pui CH; Department of Computer and Information Science, University of Pennsylvania, Philadelphia, PA, USA.
  • Evans WE; Department of Biochemistry and Molecular Genetics, Feinberg School of Medicine Northwestern University, Chicago, IL, USA.
  • Hunger SP; Department of Pathology and Laboratory Medicine, Nationwide Children's Hospital, Columbus, OH, USA.
  • Platanias LC; Department of Pediatrics, Ohio State University School of Medicine, Columbus, OH, USA.
  • Relling MV; Department of Pathology and Laboratory Medicine, Nationwide Children's Hospital, Columbus, OH, USA.
  • Mullighan CG; Department of Pediatrics, Ohio State University School of Medicine, Columbus, OH, USA.
  • Loh ML; Department of Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, TN, USA.
  • Yue F; Department of Oncology, St. Jude Children's Research Hospital, Memphis, TN, USA.
  • Yang JJ; Department of Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, TN, USA.
Nat Genet ; 54(2): 170-179, 2022 02.
Article em En | MEDLINE | ID: mdl-35115686
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Cromatina / Predisposição Genética para Doença / Polimorfismo de Nucleotídeo Único / Fator de Transcrição GATA3 / Leucemia-Linfoma Linfoblástico de Células Precursoras Tipo de estudo: Etiology_studies / Prognostic_studies / Risk_factors_studies Limite: Child / Female / Humans / Male Idioma: En Revista: Nat Genet Assunto da revista: GENETICA MEDICA Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
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Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Cromatina / Predisposição Genética para Doença / Polimorfismo de Nucleotídeo Único / Fator de Transcrição GATA3 / Leucemia-Linfoma Linfoblástico de Células Precursoras Tipo de estudo: Etiology_studies / Prognostic_studies / Risk_factors_studies Limite: Child / Female / Humans / Male Idioma: En Revista: Nat Genet Assunto da revista: GENETICA MEDICA Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Estados Unidos