Design and synthesis of the 4H-chromenone derivatives against psoriasis.

Zhang, Famin; Yan, Yaoyao; Han, Xu; Du, Jun Cheng; Zhu, Rende; Liu, Xin Hua

Zhang, Famin; Yan, Yaoyao; Han, Xu; Du, Jun Cheng; Zhu, Rende; Liu, Xin Hua.

Afiliação

Zhang F; School of Pharmacy, Anhui Province Key Laboratory of Major Autoimmune Diseases Anhui Medical University, Hefei 230032, PR China.
Yan Y; School of Pharmacy, Anhui Province Key Laboratory of Major Autoimmune Diseases Anhui Medical University, Hefei 230032, PR China.
Han X; School of Pharmacy, Anhui Province Key Laboratory of Major Autoimmune Diseases Anhui Medical University, Hefei 230032, PR China.
Du JC; School of Pharmacy, Anhui Province Key Laboratory of Major Autoimmune Diseases Anhui Medical University, Hefei 230032, PR China.
Zhu R; School of Pharmacy, Anhui Province Key Laboratory of Major Autoimmune Diseases Anhui Medical University, Hefei 230032, PR China.
Liu XH; School of Pharmacy, Anhui Province Key Laboratory of Major Autoimmune Diseases Anhui Medical University, Hefei 230032, PR China. Electronic address: xhliuhx@163.com.

Bioorg Chem ; 120: 105640, 2022 03.

Article em En | MEDLINE | ID: mdl-35121555

Assuntos

Interleucina-17; Psoríase; Animais; Modelos Animais de Doenças; Imiquimode/efeitos adversos; Interleucina-17/efeitos adversos; Camundongos; Camundongos Endogâmicos BALB C; Psoríase/induzido quimicamente; Psoríase/tratamento farmacológico; Fator de Necrose Tumoral alfa/metabolismo

Palavras-chave

4H-chromenone derivative; Anti-inflammatory activity; JAK1/2-STAT1/3 pathway; Psoriasis

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Psoríase / Interleucina-17 Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Bioorg Chem Ano de publicação: 2022 Tipo de documento: Article

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