Some guidelines for identification of recognition sequences: regulatory sequences frequently contain (T)GTG/CAC(A), TGA/TCA and (T)CTC/GAG(A).
Biochim Biophys Acta
; 866(2-3): 93-108, 1986 Mar 26.
Article
em En
| MEDLINE
| ID: mdl-3513842
ABSTRACT
Inspection of many proposed recognition signal sequences shows that TGTG/CACA, GAGA/TCTC or their triplet subsets, and TGA/TCA occur frequently. These repeated elements, conserved in recognition sequences from evolutionarily distant organisms, are likely to possess unique structural characteristics. Recurrence of these oligomers may aid in identification of further regulatory sequences in upstream or other regions. Another class of recognition sequences is GC-rich. At present there are only a few examples of this class. It is likely that these sequences function via a different mechanism.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Genes Reguladores
Tipo de estudo:
Diagnostic_studies
/
Guideline
/
Prognostic_studies
Limite:
Animals
/
Humans
Idioma:
En
Revista:
Biochim Biophys Acta
Ano de publicação:
1986
Tipo de documento:
Article