RNA-assisted sequestration of RNA-binding proteins by cytoplasmic inclusions of the C-terminal 35-kDa fragment of TDP-43.

Jiang, Lei-Lei; Guan, Wen-Liang; Wang, Jian-Yang; Zhang, Shu-Xian; Hu, Hong-Yu

Jiang, Lei-Lei; Guan, Wen-Liang; Wang, Jian-Yang; Zhang, Shu-Xian; Hu, Hong-Yu.

Afiliação

Jiang LL; State Key Laboratory of Molecular Biology, Shanghai Institute of Biochemistry and Cell Biology, Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences, Shanghai 200031, P. R. China.
Guan WL; State Key Laboratory of Molecular Biology, Shanghai Institute of Biochemistry and Cell Biology, Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences, Shanghai 200031, P. R. China.
Wang JY; University of Chinese Academy of Sciences, Beijing 100049, P. R. China.
Zhang SX; State Key Laboratory of Molecular Biology, Shanghai Institute of Biochemistry and Cell Biology, Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences, Shanghai 200031, P. R. China.
Hu HY; University of Chinese Academy of Sciences, Beijing 100049, P. R. China.

J Cell Sci ; 135(6)2022 03 15.

Article em En | MEDLINE | ID: mdl-35142363

Assuntos

Esclerose Lateral Amiotrófica; Proteinopatias TDP-43; Esclerose Lateral Amiotrófica/metabolismo; Proteínas de Ligação a DNA/metabolismo; Humanos; Corpos de Inclusão/metabolismo; RNA/genética; RNA/metabolismo; Precursores de RNA/metabolismo; Proteínas de Ligação a RNA/genética; Proteínas de Ligação a RNA/metabolismo; Proteinopatias TDP-43/metabolismo

Palavras-chave

Cytoplasmic inclusion; Live-cell imaging; RNA-assisted sequestration; RNA-binding protein; TDP-43; TIA1

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteinopatias TDP-43 / Esclerose Lateral Amiotrófica Limite: Humans Idioma: En Revista: J Cell Sci Ano de publicação: 2022 Tipo de documento: Article

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