Molecular Mechanisms of Malignant Transformation of Oral Submucous Fibrosis by Different Betel Quid Constituents-Does Fibroblast Senescence Play a Role?

Zhang, Pangzhen; Chua, Nathaniel Quan En; Dang, Simon; Davis, Ashleigh; Chong, Kah Wee; Prime, Stephen S; Cirillo, Nicola

Zhang, Pangzhen; Chua, Nathaniel Quan En; Dang, Simon; Davis, Ashleigh; Chong, Kah Wee; Prime, Stephen S; Cirillo, Nicola.

Afiliação

Zhang P; School of Agriculture and Food, Faculty of Veterinary and Agricultural Sciences, The University of Melbourne, Parkville, VIC 3052, Australia.
Chua NQE; Melbourne Dental School, Faculty of Medicine, Dentistry and Health Sciences, The University of Melbourne, Carlton, VIC 3053, Australia.
Dang S; Melbourne Dental School, Faculty of Medicine, Dentistry and Health Sciences, The University of Melbourne, Carlton, VIC 3053, Australia.
Davis A; Melbourne Dental School, Faculty of Medicine, Dentistry and Health Sciences, The University of Melbourne, Carlton, VIC 3053, Australia.
Chong KW; Melbourne Dental School, Faculty of Medicine, Dentistry and Health Sciences, The University of Melbourne, Carlton, VIC 3053, Australia.
Prime SS; Centre for Immunology and Regenerative Medicine, Institute of Dentistry, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London E1 4NS, UK.
Cirillo N; Melbourne Dental School, Faculty of Medicine, Dentistry and Health Sciences, The University of Melbourne, Carlton, VIC 3053, Australia.

Int J Mol Sci ; 23(3)2022 Jan 31.

Article em En | MEDLINE | ID: mdl-35163557

Assuntos

Areca/química; Carcinoma de Células Escamosas/induzido quimicamente; Neoplasias Bucais/induzido quimicamente; Fibrose Oral Submucosa/induzido quimicamente; Extratos Vegetais/efeitos adversos; Arecolina/efeitos adversos; Arecolina/análogos & derivados; Carcinoma de Células Escamosas/patologia; Progressão da Doença; Humanos; Neoplasias Bucais/patologia; Ácidos Nicotínicos/efeitos adversos; Fibrose Oral Submucosa/patologia

Palavras-chave

areca nut; arecoline; betel quid; carcinogenic potential; fibroblast senescence; oral carcinogenesis; oral submucous fibrosis

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fibrose Oral Submucosa / Areca / Neoplasias Bucais / Extratos Vegetais / Carcinoma de Células Escamosas Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Int J Mol Sci Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Austrália

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