Exercise increases the lung clearance of inhaled technetium-99m DTPA.
J Nucl Med
; 27(2): 274-80, 1986 Feb.
Article
em En
| MEDLINE
| ID: mdl-3519893
ABSTRACT
The regional lung clearance of a deposited aerosol of [99mTc] diethylenetriaminepentaacetic acid was successively computed at rest and at exercise in seven nonsmoking volunteers in upright posture. The subjects were seated on a bicycle with their backs against a gamma camera. At rest there was a gradient of clearance from the apex to the base of the lung, the apical clearance being significantly higher. At exercise this regional gradient was enhanced by a large and significant increase of the apical clearances (3.40 +/- 0.63% min-1 s.d. compared with 1.82 +/- 0.75% min-1 s.d. at rest, n = 7, p less than 0.01). By contrast the changes of the basal clearances were slight and unsignificant (1.46 +/- 0.71% min-1 s.d. compared with 1.40 +/- 0.82% min-1 s.d.). This increase of the apical lung clearance could be attributed primarily to the increase of apical blood flow induced by exercise and to the subsequent increase of the permeability surface area product.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Tecnécio
/
Ácido Pentético
/
Esforço Físico
/
Pulmão
Limite:
Adult
/
Female
/
Humans
/
Male
Idioma:
En
Revista:
J Nucl Med
Ano de publicação:
1986
Tipo de documento:
Article