Development of a rapid and sensitive LC-MS/MS assay for the quantiï¬cation of commonly abused drugs in Asia in a micro-segment of a single hair using microwave-assisted extraction and dansyl chloride derivatization.

Chen, Hsiu-Chuan; Lee, Pin-Duo; Chang, Yan-Zin

Development of a rapid and sensitive LC-MS/MS assay for the quantiï¬cation of commonly abused drugs in Asia in a micro-segment of a single hair using microwave-assisted extraction and dansyl chloride derivatization.

Chen, Hsiu-Chuan; Lee, Pin-Duo; Chang, Yan-Zin.

Afiliação

Chen HC; Institute of Medicine, Chung Shan Medical University, Taichung 40201, Taiwan.
Lee PD; Institute of Medicine, Chung Shan Medical University, Taichung 40201, Taiwan.
Chang YZ; Institute of Medicine, Chung Shan Medical University, Taichung 40201, Taiwan; Drug Testing Center, Department of Clinical Laboratory, Chung Shan Medical University Hospital, Taichung 40201, Taiwan. Electronic address: yzc@csmu.edu.tw.

J Pharm Biomed Anal ; 213: 114678, 2022 May 10.

Article em En | MEDLINE | ID: mdl-35257983

Assuntos

Drogas Ilícitas; Espectrometria de Massas em Tandem; Anfetamina; Cromatografia Líquida; Compostos de Dansil; Cabelo/química; Drogas Ilícitas/análise; Micro-Ondas; Detecção do Abuso de Substâncias/métodos; Espectrometria de Massas em Tandem/métodos

Palavras-chave

Dansyl chloride; Drugs of abuse; Hair; LC-MS/MS; Segmental analysis

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Drogas Ilícitas / Espectrometria de Massas em Tandem Tipo de estudo: Diagnostic_studies Idioma: En Revista: J Pharm Biomed Anal Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Taiwan

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