PSMD14 Targeting Triggers Paraptosis in Breast Cancer Cells by Inducing Proteasome Inhibition and Ca<sup>2+</sup> Imbalance.

Lee, Hong-Jae; Lee, Dong-Min; Seo, Min-Ji; Kang, Ho-Chul; Kwon, Seok-Kyu; Choi, Kyeong-Sook

PSMD14 Targeting Triggers Paraptosis in Breast Cancer Cells by Inducing Proteasome Inhibition and Ca²⁺ Imbalance.

Lee, Hong-Jae; Lee, Dong-Min; Seo, Min-Ji; Kang, Ho-Chul; Kwon, Seok-Kyu; Choi, Kyeong-Sook.

Afiliação

Lee HJ; Department of Biochemistry and Molecular Biology, Ajou University, Suwon 16499, Korea.
Lee DM; Department of Biochemistry and Molecular Biology, Ajou University, Suwon 16499, Korea.
Seo MJ; Department of Biochemistry and Molecular Biology, Ajou University, Suwon 16499, Korea.
Kang HC; Department of Physiology, Ajou University School of Medicine, Suwon 16499, Korea.
Kwon SK; Brain Science Institute, Korea Institute of Science and Technology (KIST), Seoul 02792, Korea.
Choi KS; Division of Bio-Medical Science & Technology, KIST School, Korea University of Science & Technology (UST), Daejeon 34113, Korea.

Int J Mol Sci ; 23(5)2022 Feb 28.

Article em En | MEDLINE | ID: mdl-35269789

Assuntos

Neoplasias da Mama; Cálcio/metabolismo; Complexo de Endopeptidases do Proteassoma; Apoptose; Bortezomib/farmacologia; Neoplasias da Mama/tratamento farmacológico; Linhagem Celular Tumoral; Feminino; Humanos; Complexo de Endopeptidases do Proteassoma/metabolismo; Inibidores de Proteassoma/farmacologia; Transativadores

Palavras-chave

Ca2+ imbalance; PSMD14; paraptosis; proteasome; proteostasis

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias da Mama / Cálcio / Complexo de Endopeptidases do Proteassoma Tipo de estudo: Prognostic_studies Limite: Female / Humans Idioma: En Revista: Int J Mol Sci Ano de publicação: 2022 Tipo de documento: Article

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