Fludarabine increases nuclease-free AAV- and CRISPR/Cas9-mediated homologous recombination in mice.

Tsuji, Shinnosuke; Stephens, Calvin J; Bortolussi, Giulia; Zhang, Feijie; Baj, Gabriele; Jang, Hagoon; de Alencastro, Gustavo; Muro, Andrés F; Pekrun, Katja; Kay, Mark A

Tsuji, Shinnosuke; Stephens, Calvin J; Bortolussi, Giulia; Zhang, Feijie; Baj, Gabriele; Jang, Hagoon; de Alencastro, Gustavo; Muro, Andrés F; Pekrun, Katja; Kay, Mark A.

Afiliação

Tsuji S; Departments of Pediatrics and Genetics, Stanford University, Stanford, CA, USA.
Stephens CJ; Departments of Pediatrics and Genetics, Stanford University, Stanford, CA, USA.
Bortolussi G; International Centre for Genetic Engineering and Biotechnology (ICGEB), Trieste, Italy.
Zhang F; Departments of Pediatrics and Genetics, Stanford University, Stanford, CA, USA.
Baj G; Light Microscopy Imaging Center, Department of Life Sciences, University of Trieste, Trieste, Italy.
Jang H; Departments of Pediatrics and Genetics, Stanford University, Stanford, CA, USA.
de Alencastro G; Departments of Pediatrics and Genetics, Stanford University, Stanford, CA, USA.
Muro AF; International Centre for Genetic Engineering and Biotechnology (ICGEB), Trieste, Italy.
Pekrun K; Departments of Pediatrics and Genetics, Stanford University, Stanford, CA, USA.
Kay MA; Departments of Pediatrics and Genetics, Stanford University, Stanford, CA, USA. markay@stanford.edu.

Nat Biotechnol ; 40(8): 1285-1294, 2022 08.

Article em En | MEDLINE | ID: mdl-35393561

Assuntos

Sistemas CRISPR-Cas; Vetores Genéticos; Animais; Sistemas CRISPR-Cas/genética; Dependovirus/genética; Endonucleases/genética; Edição de Genes/métodos; Recombinação Homóloga; Humanos; Camundongos; Vidarabina/análogos & derivados

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Sistemas CRISPR-Cas / Vetores Genéticos Limite: Animals / Humans Idioma: En Revista: Nat Biotechnol Assunto da revista: BIOTECNOLOGIA Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Estados Unidos

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