Hypoxia inducible lncRNA-CBSLR modulates ferroptosis through m6A-YTHDF2-dependent modulation of CBS in gastric cancer.

Yang, Hui; Hu, Yiren; Weng, Mingzhe; Liu, Xiaocen; Wan, Ping; Hu, Ye; Ma, Mingzhe; Zhang, Yan; Xia, Hongping; Lv, Kun

Yang, Hui; Hu, Yiren; Weng, Mingzhe; Liu, Xiaocen; Wan, Ping; Hu, Ye; Ma, Mingzhe; Zhang, Yan; Xia, Hongping; Lv, Kun.

Afiliação

Yang H; Key Laboratory of Non-coding RNA Transformation Research of Anhui Higher Education Institution (Wannan Medical College), Wuhu, Anhui 241001, China.
Hu Y; Central Laboratory, Yijishan Hospital, The First Affiliated Hospital of Wannan Medical College, Wuhu, Anhui 241001, China.
Weng M; Key Laboratory of Non-coding RNA Transformation Research of Anhui Higher Education Institution (Wannan Medical College), Wuhu, Anhui 241001, China.
Liu X; Department of General Surgery, Wenzhou No.3 Clinical Institute of Wenzhou Medical University, Wenzhou People's Hospital, Wenzhou, Zhejiang 325000, China.
Wan P; Key Laboratory of Non-coding RNA Transformation Research of Anhui Higher Education Institution (Wannan Medical College), Wuhu, Anhui 241001, China.
Hu Y; Department of General Surgery, Xinhua Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai 200032, China.
Ma M; Key Laboratory of Non-coding RNA Transformation Research of Anhui Higher Education Institution (Wannan Medical College), Wuhu, Anhui 241001, China.
Zhang Y; Department of Nuclear Medicine, Yijishan Hospital, The First Affiliated Hospital of Wannan Medical College, Wuhu, Anhui 241001, China.
Xia H; Key Laboratory of Non-coding RNA Transformation Research of Anhui Higher Education Institution (Wannan Medical College), Wuhu, Anhui 241001, China.
Lv K; Department of Liver Surgery, Renji Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai 200032, China.

J Adv Res ; 37: 91-106, 2022 03.

Article em En | MEDLINE | ID: mdl-35499052

Assuntos

Ferroptose; RNA Longo não Codificante; Neoplasias Gástricas; Humanos; Hipóxia; RNA Longo não Codificante/genética; RNA Mensageiro/genética; RNA Mensageiro/metabolismo; Proteínas de Ligação a RNA/genética; Proteínas de Ligação a RNA/metabolismo; Neoplasias Gástricas/genética; Neoplasias Gástricas/patologia; Fatores de Transcrição/metabolismo

Palavras-chave

4-HNE, 4-hydroxynonenal; AJCC, American Joint Committee on Cancer; CDS, coding sequence; CHIP, chromatin immunoprecipitation; Chemoresistance; DZNeP, 3-deazaneplanocin A; FBS, fetal bovine serum; Ferroptosis; GC, gastric cancer; GEO, Gene Expression Omnibus; Gastric cancer; HE, Hematoxylin and eosin; HREs, hypoxia response elements; Hypoxia; IHC, immunohistochemical; MDA, malondialdehyde; RIP, RNA immunoprecipitation; TCGA, the cancer genome atlas; TNM, tumor-node-metastasis staging system; YTHDF2, YTH domain family protein 2; lncRNA; lncRNA, long noncoding RNA; qPCR, quantitative real-time PCR

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Gástricas / RNA Longo não Codificante / Ferroptose Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: J Adv Res Ano de publicação: 2022 Tipo de documento: Article País de afiliação: China

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