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Iron accumulation induces oxidative stress, while depressing inflammatory polarization in human iPSC-derived microglia.
Kenkhuis, Boyd; van Eekeren, Michelle; Parfitt, David A; Ariyurek, Yavuz; Banerjee, Poulomi; Priller, Josef; van der Weerd, Louise; van Roon-Mom, Willeke M C.
Afiliação
  • Kenkhuis B; Department of Human Genetics, Leiden University Medical Center, Postzone S4-0P, P.O. Box 9600, 2300RC Leiden, the Netherlands; Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, UK; UK Dementia Research Institute at University of Edinburgh, Edinburgh, UK. Electronic address: b.k
  • van Eekeren M; Department of Human Genetics, Leiden University Medical Center, Postzone S4-0P, P.O. Box 9600, 2300RC Leiden, the Netherlands.
  • Parfitt DA; Department of Human Genetics, Leiden University Medical Center, Postzone S4-0P, P.O. Box 9600, 2300RC Leiden, the Netherlands.
  • Ariyurek Y; Leiden Genome Technology Center, Leiden University Medical Center, Leiden, the Netherlands.
  • Banerjee P; Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, UK; UK Dementia Research Institute at University of Edinburgh, Edinburgh, UK.
  • Priller J; Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, UK; UK Dementia Research Institute at University of Edinburgh, Edinburgh, UK; Department of Psychiatry and Psychotherapy, School of Medicine, Technical University of Munich, Munich, Germany; Neuropsychiatry and Laboratory of Mol
  • van der Weerd L; Department of Human Genetics, Leiden University Medical Center, Postzone S4-0P, P.O. Box 9600, 2300RC Leiden, the Netherlands; Department of Radiology, Leiden University Medical Center, Leiden, the Netherlands.
  • van Roon-Mom WMC; Department of Human Genetics, Leiden University Medical Center, Postzone S4-0P, P.O. Box 9600, 2300RC Leiden, the Netherlands.
Stem Cell Reports ; 17(6): 1351-1365, 2022 06 14.
Article em En | MEDLINE | ID: mdl-35523178
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Microglia / Células-Tronco Pluripotentes Induzidas Limite: Humans Idioma: En Revista: Stem Cell Reports Ano de publicação: 2022 Tipo de documento: Article
Texto completo
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XML
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Microglia / Células-Tronco Pluripotentes Induzidas Limite: Humans Idioma: En Revista: Stem Cell Reports Ano de publicação: 2022 Tipo de documento: Article