Effect of dietary n-6: n-3 Poly-Unsaturated fatty acids ratio on gestational diabetes mellitus: a prospective cohort.
Gynecol Endocrinol
; 38(7): 583-587, 2022 Jul.
Article
em En
| MEDLINE
| ID: mdl-35549805
ABSTRACT
OBJECTIVE:
The aim of this study was to investigate the relationship between dietary n-6 n-3 poly-unsaturated fatty acids (PUFA) ratio and the risk of developing gestational diabetes mellitus (GDM). MATERIALS ANDMETHODS:
A total of 100 pregnant women were prospectively included for detailed information on dietary intake at 16-18 weeks evaluated using a three-day food record, and subsequent GDM diagnosis at 24-28 weeks. Participants were divided into two groups foranalysis:
GDM group (n = 22) and control group (n = 78) based on oral glucose tolerance test results performed between 24 and 28 weeks.RESULTS:
The average dietary n-6 n-3 PUFA ratio in the control group was 5.63 ± 2.12 and that in the GDM group was 8.35 ± 3.45, within a significant difference (p < .05). A significant difference was associated with a higher dietary n-6 n-3 PUFA ratio and GDM (adjusted odds ratio = 4.29, 95%confidence interval1.303, 14.124).CONCLUSIONS:
Higher dietary n-6 n-3 PUFA ratio was associated with higher odds of GDM. Given the small sample, further studies are required to confirm this hypothesis.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Ácidos Graxos Ômega-3
/
Diabetes Gestacional
Tipo de estudo:
Observational_studies
/
Risk_factors_studies
Limite:
Female
/
Humans
/
Pregnancy
Idioma:
En
Revista:
Gynecol Endocrinol
Assunto da revista:
ENDOCRINOLOGIA
/
GINECOLOGIA
Ano de publicação:
2022
Tipo de documento:
Article
País de afiliação:
China