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Can metformin relieve tibiofemoral cartilage volume loss and knee symptoms in overweight knee osteoarthritis patients? Study protocol for a randomized, double-blind, and placebo-controlled trial.
Ruan, Guangfeng; Yuan, Shiwen; Lou, Aiju; Mo, Yingqian; Qu, Yuan; Guo, Dongmei; Guan, Shangqi; Zhang, Yan; Lan, Xiaoyong; Luo, Jun; Mei, Yifang; Zhang, Hongwei; Wu, Weirong; Dai, Lie; Yu, Qinghong; Cai, Xiaoyan; Ding, Changhai.
Afiliação
  • Ruan G; Clinical Research Centre, Guangzhou First People's Hospital, School of Medicine, South China University of Technology, Guangzhou, China.
  • Yuan S; Clinical Research Centre, Zhujiang Hospital, Southern Medical University, Guangzhou, Guangdong, China.
  • Lou A; Department of Rheumatology, Guangzhou First People's Hospital, School of Medicine, South China University of Technology, Guangzhou, Guangdong, China.
  • Mo Y; Department of Rheumatology and Immunology, Liwan Central Hospital of Guangzhou, Guangzhou, Guangdong, China.
  • Qu Y; Department of Rheumatology, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, Guangdong, China.
  • Guo D; Rheumatology and Clinical Immunology Department, Zhujiang Hospital, Southern Medical University, Guangzhou, Guangdong, China.
  • Guan S; Department of Rheumatology, Foshan First People's Hospital, Foshan, Guangdong, China.
  • Zhang Y; Department of Rheumatology, Third People's Hospital of Shenzhen, The Second Affiliated Hospital of Southern University of Science and Technology, Shenzhen, Guangdong, China.
  • Lan X; Clinical Research Centre, Zhujiang Hospital, Southern Medical University, Guangzhou, Guangdong, China.
  • Luo J; Department of Rehabilitation Medicine, the Second Affiliated Hospital of Nanchang University, Nanchang, Jiangxi, China.
  • Mei Y; Department of Rehabilitation Medicine, the Second Affiliated Hospital of Nanchang University, Nanchang, Jiangxi, China.
  • Zhang H; Department of Rheumatology, Third People's Hospital of Shenzhen, The Second Affiliated Hospital of Southern University of Science and Technology, Shenzhen, Guangdong, China.
  • Wu W; Department of Rheumatology, Foshan First People's Hospital, Foshan, Guangdong, China.
  • Dai L; Department of Rheumatology and Immunology, Liwan Central Hospital of Guangzhou, Guangzhou, Guangdong, China.
  • Yu Q; Department of Rheumatology, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, Guangdong, China.
  • Cai X; Rheumatology and Clinical Immunology Department, Zhujiang Hospital, Southern Medical University, Guangzhou, Guangdong, China.
  • Ding C; Department of Rheumatology, Guangzhou First People's Hospital, School of Medicine, South China University of Technology, Guangzhou, Guangdong, China. caixytracy@126.com.
BMC Musculoskelet Disord ; 23(1): 486, 2022 May 21.
Article em En | MEDLINE | ID: mdl-35598008

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Osteoartrite do Joelho / Diabetes Mellitus Tipo 2 / Metformina Tipo de estudo: Clinical_trials / Diagnostic_studies / Guideline / Observational_studies Limite: Humans Idioma: En Revista: BMC Musculoskelet Disord Assunto da revista: FISIOLOGIA / ORTOPEDIA Ano de publicação: 2022 Tipo de documento: Article País de afiliação: China

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Osteoartrite do Joelho / Diabetes Mellitus Tipo 2 / Metformina Tipo de estudo: Clinical_trials / Diagnostic_studies / Guideline / Observational_studies Limite: Humans Idioma: En Revista: BMC Musculoskelet Disord Assunto da revista: FISIOLOGIA / ORTOPEDIA Ano de publicação: 2022 Tipo de documento: Article País de afiliação: China