Design principles of PI(4,5)P<sub>2</sub> clustering under protein-free conditions: Specific cation effects and calcium-potassium synergy.

Han, Kyungreem; Kim, Soon Ho; Venable, Richard M; Pastor, Richard W

Design principles of PI(4,5)P₂ clustering under protein-free conditions: Specific cation effects and calcium-potassium synergy.

Han, Kyungreem; Kim, Soon Ho; Venable, Richard M; Pastor, Richard W.

Afiliação

Han K; Laboratory of Computational Biology, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, MD 20892.
Kim SH; Laboratory of Computational Neurophysics, Convergence Research Center for Brain Science, Brain Science Institute, Korea Institute of Science and Technology, Seoul 02792, Korea.
Venable RM; Laboratory of Computational Neurophysics, Convergence Research Center for Brain Science, Brain Science Institute, Korea Institute of Science and Technology, Seoul 02792, Korea.
Pastor RW; Laboratory of Computational Biology, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, MD 20892.

Proc Natl Acad Sci U S A ; 119(22): e2202647119, 2022 05 31.

Article em En | MEDLINE | ID: mdl-35605121

Assuntos

Cálcio; Fosfatidilinositol 4,5-Difosfato; Transdução de Sinais; Cálcio/metabolismo; Cátions; Peptídeos e Proteínas de Sinalização Intracelular; Canais Iônicos; Fosfatos; Fosfatidilinositol 4,5-Difosfato/metabolismo; Potássio

Palavras-chave

PI(4,5)P2 clustering; all-atom molecular dynamics; network theory; specific ion effects

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Transdução de Sinais / Cálcio / Fosfatidilinositol 4,5-Difosfato Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2022 Tipo de documento: Article

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