TGF-ß1 receptor blockade attenuates unilateral ureteral obstruction-induced renal fibrosis in C57BL/6 mice through attenuating Smad and MAPK pathways.

Nazari Soltan Ahmad, Saeed; Kalantary-Charvadeh, Ashkan; Hamzavi, Masoud; Ezzatifar, Fatemeh; Aboutalebi Vand Beilankouhi, Elmira; Toofani-Milani, Attabak; Geravand, Faezeh; Golshadi, Zakieh; Mesgari-Abbasi, Mehran

Nazari Soltan Ahmad, Saeed; Kalantary-Charvadeh, Ashkan; Hamzavi, Masoud; Ezzatifar, Fatemeh; Aboutalebi Vand Beilankouhi, Elmira; Toofani-Milani, Attabak; Geravand, Faezeh; Golshadi, Zakieh; Mesgari-Abbasi, Mehran.

Afiliação

Nazari Soltan Ahmad S; Drug Applied Research Center, Tabriz University of Medical Sciences, Golgasht Avenue, Tabriz, Iran.
Kalantary-Charvadeh A; Department of Clinical Biochemistry, Faculty of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran.
Hamzavi M; Department of Food Science and Technology, Faculty of Nutrition and Food Technology, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Ezzatifar F; Department of Immunology, School of Medicine, Mazandaran University of Medical Sciences, Sari, Iran.
Aboutalebi Vand Beilankouhi E; Immunology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Toofani-Milani A; Department of Medical Laboratory Sciences and Microbiology, Faculty of Medicine, Tabriz Medical Sciences, Islamic Azad University, Tabriz, Iran.
Geravand F; Department of Nutrition, Bushehr University of Medical Sciences, Bushehr, Iran.
Golshadi Z; Student Research Committee, Qazvin University of Medical Sciences, Qazvin, Iran.
Mesgari-Abbasi M; Drug Applied Research Center, Tabriz University of Medical Sciences, Golgasht Avenue, Tabriz, Iran. mesgarim@tbzmed.ac.ir.

J Mol Histol ; 53(4): 691-698, 2022 Aug.

Article em En | MEDLINE | ID: mdl-35704228

Assuntos

Nefropatias; Obstrução Ureteral; Animais; Fibrose; Rim/patologia; Nefropatias/tratamento farmacológico; Nefropatias/etiologia; Nefropatias/metabolismo; Masculino; Camundongos; Camundongos Endogâmicos C57BL; Transdução de Sinais; Fator de Crescimento Transformador beta1/metabolismo; Obstrução Ureteral/complicações; Obstrução Ureteral/tratamento farmacológico; Obstrução Ureteral/metabolismo

Palavras-chave

Galunisertib; Kidney fibrosis; LY-2157299; Transforming growth factor beta; UUO model

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Obstrução Ureteral / Nefropatias Tipo de estudo: Etiology_studies / Prognostic_studies Limite: Animals Idioma: En Revista: J Mol Histol Assunto da revista: HISTOCITOQUIMICA Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Irã

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google