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STAT1 is essential for HSC function and maintains MHCIIhi stem cells that resist myeloablation and neoplastic expansion.
Li, Juan; Williams, Matthew J; Park, Hyun Jung; Bastos, Hugo P; Wang, Xiaonan; Prins, Daniel; Wilson, Nicola K; Johnson, Carys; Sham, Kendig; Wantoch, Michelle; Watcham, Sam; Kinston, Sarah J; Pask, Dean C; Hamilton, Tina L; Sneade, Rachel; Waller, Amie K; Ghevaert, Cedric; Vassiliou, George S; Laurenti, Elisa; Kent, David G; Göttgens, Berthold; Green, Anthony R.
Afiliação
  • Li J; Wellcome-Medical Research Council Cambridge Stem Cell Institute, Jeffrey Cheah Biomedical Centre, Cambridge, United Kingdom.
  • Williams MJ; Department of Haematology, University of Cambridge, Cambridge, United Kingdom.
  • Park HJ; Wellcome-Medical Research Council Cambridge Stem Cell Institute, Jeffrey Cheah Biomedical Centre, Cambridge, United Kingdom.
  • Bastos HP; Department of Haematology, University of Cambridge, Cambridge, United Kingdom.
  • Wang X; Wellcome-Medical Research Council Cambridge Stem Cell Institute, Jeffrey Cheah Biomedical Centre, Cambridge, United Kingdom.
  • Prins D; Department of Haematology, University of Cambridge, Cambridge, United Kingdom.
  • Wilson NK; Wellcome-Medical Research Council Cambridge Stem Cell Institute, Jeffrey Cheah Biomedical Centre, Cambridge, United Kingdom.
  • Johnson C; Department of Haematology, University of Cambridge, Cambridge, United Kingdom.
  • Sham K; Wellcome-Medical Research Council Cambridge Stem Cell Institute, Jeffrey Cheah Biomedical Centre, Cambridge, United Kingdom.
  • Wantoch M; Department of Haematology, University of Cambridge, Cambridge, United Kingdom.
  • Watcham S; Wellcome-Medical Research Council Cambridge Stem Cell Institute, Jeffrey Cheah Biomedical Centre, Cambridge, United Kingdom.
  • Kinston SJ; Department of Haematology, University of Cambridge, Cambridge, United Kingdom.
  • Pask DC; Wellcome-Medical Research Council Cambridge Stem Cell Institute, Jeffrey Cheah Biomedical Centre, Cambridge, United Kingdom.
  • Hamilton TL; Department of Haematology, University of Cambridge, Cambridge, United Kingdom.
  • Sneade R; Wellcome-Medical Research Council Cambridge Stem Cell Institute, Jeffrey Cheah Biomedical Centre, Cambridge, United Kingdom.
  • Waller AK; Department of Haematology, University of Cambridge, Cambridge, United Kingdom.
  • Ghevaert C; Wellcome-Medical Research Council Cambridge Stem Cell Institute, Jeffrey Cheah Biomedical Centre, Cambridge, United Kingdom.
  • Vassiliou GS; Department of Haematology, University of Cambridge, Cambridge, United Kingdom.
  • Laurenti E; Wellcome-Medical Research Council Cambridge Stem Cell Institute, Jeffrey Cheah Biomedical Centre, Cambridge, United Kingdom.
  • Kent DG; Department of Haematology, University of Cambridge, Cambridge, United Kingdom.
  • Göttgens B; Wellcome-Medical Research Council Cambridge Stem Cell Institute, Jeffrey Cheah Biomedical Centre, Cambridge, United Kingdom.
  • Green AR; Department of Haematology, University of Cambridge, Cambridge, United Kingdom.
Blood ; 140(14): 1592-1606, 2022 10 06.
Article em En | MEDLINE | ID: mdl-35767701
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Células-Tronco Hematopoéticas / Megacariócitos / Fator de Transcrição STAT1 Limite: Animals / Humans Idioma: En Revista: Blood Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Reino Unido
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Células-Tronco Hematopoéticas / Megacariócitos / Fator de Transcrição STAT1 Limite: Animals / Humans Idioma: En Revista: Blood Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Reino Unido