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Colocalized targeting of TGF-ß and PD-L1 by bintrafusp alfa elicits distinct antitumor responses.
Lan, Yan; Yeung, Tsz-Lun; Huang, Hui; Wegener, Ansgar A; Saha, Somdutta; Toister-Achituv, Mira; Jenkins, Molly H; Chiu, Li-Ya; Lazorchak, Adam; Tarcic, Ohad; Wang, Hong; Qi, Jin; Locke, George; Kalimi, Doron; Qin, Guozhong; Marelli, Bo; Yu, Huakui; Gross, Alec W; Derner, Melissa G; Soloviev, Maria; Botte, Mathieu; Sircar, Aroop; Ma, Hong; Sood, Vanita D; Zhang, Dong; Jiang, Feng; Lo, Kin-Ming.
Afiliação
  • Lan Y; Department of TIP OIO, EMD Serono Research and Development Institute, Billerica, Massachusetts, USA yan.lan@emdserono.com kinming.lo@emdserono.com.
  • Yeung TL; Department of TIP OIO, EMD Serono Research and Development Institute, Billerica, Massachusetts, USA.
  • Huang H; Department of TIP OIO, EMD Serono Research and Development Institute, Billerica, Massachusetts, USA.
  • Wegener AA; Department of Discovery and Development Technologies, Merck Healthcare KGaA, Darmstadt, Germany.
  • Saha S; Department of Translational Medicine, EMD Serono Research and Development Institute, Billerica, Massachusetts, USA.
  • Toister-Achituv M; Department of Discovery and Development Technologies, Merck Healthcare KGaA, Yavne, Israel.
  • Jenkins MH; Department of TIP OIO, EMD Serono Research and Development Institute, Billerica, Massachusetts, USA.
  • Chiu LY; Department of TIP OIO, EMD Serono Research and Development Institute, Billerica, Massachusetts, USA.
  • Lazorchak A; Department of TIP OIO, EMD Serono Research and Development Institute, Billerica, Massachusetts, USA.
  • Tarcic O; Be Biopharma, Cambridge, Massachusetts, USA.
  • Wang H; Department of Discovery and Development Technologies, Merck Healthcare KGaA, Yavne, Israel.
  • Qi J; CAVOS Biotech, Jerusalem, Israel.
  • Locke G; Department of TIP OIO, EMD Serono Research and Development Institute, Billerica, Massachusetts, USA.
  • Kalimi D; Department of TIP OIO, EMD Serono Research and Development Institute, Billerica, Massachusetts, USA.
  • Qin G; Department of Translational Medicine, EMD Serono Research and Development Institute, Billerica, Massachusetts, USA.
  • Marelli B; Department of Discovery and Development Technologies, Merck Healthcare KGaA, Yavne, Israel.
  • Yu H; Department of TIP OIO, EMD Serono Research and Development Institute, Billerica, Massachusetts, USA.
  • Gross AW; Department of TIP OIO, EMD Serono Research and Development Institute, Billerica, Massachusetts, USA.
  • Derner MG; Department of TIP OIO, EMD Serono Research and Development Institute, Billerica, Massachusetts, USA.
  • Soloviev M; Department of Discovery Development Technologies, EMD Serono Research and Development Institute, Billerica, Massachusetts, USA.
  • Botte M; Department of TIP OIO, EMD Serono Research and Development Institute, Billerica, Massachusetts, USA.
  • Sircar A; Department of Discovery Development Technologies, EMD Serono Research and Development Institute, Billerica, Massachusetts, USA.
  • Ma H; LeadXPro AG, Villigen, Switzerland.
  • Sood VD; Department of TIP OIO, EMD Serono Research and Development Institute, Billerica, Massachusetts, USA.
  • Zhang D; Department of Integrated Supply Chain Operations, EMD Serono Research and Development Institute, Billerica, Massachusetts, USA.
  • Jiang F; Department of Discovery Development Technologies, EMD Serono Research and Development Institute, Billerica, Massachusetts, USA.
  • Lo KM; Department of TIP OIO, EMD Serono Research and Development Institute, Billerica, Massachusetts, USA.
J Immunother Cancer ; 10(7)2022 07.
Article em En | MEDLINE | ID: mdl-35858707
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fator de Crescimento Transformador beta / Neoplasias Pulmonares Limite: Humans Idioma: En Revista: J Immunother Cancer Ano de publicação: 2022 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fator de Crescimento Transformador beta / Neoplasias Pulmonares Limite: Humans Idioma: En Revista: J Immunother Cancer Ano de publicação: 2022 Tipo de documento: Article