Cost analysis of the enhanced recovery after surgery protocol applied in advanced ovarian cancer: A secondary outcome of the PROFAST trial.
Eur J Surg Oncol
; 48(12): 2545-2550, 2022 Dec.
Article
em En
| MEDLINE
| ID: mdl-35922279
ABSTRACT
INTRODUCTION:
A randomised trial implementing Enhanced Recovery After Surgery (ERAS) for high complexity advanced ovarian cancer (AOC) surgery (PROFAST) demonstrated a reduction of median length of stay and hospital readmissions when compared to patients managed conventionally. One secondary objective was to determine if an ERAS pathway in the perioperative management of advanced ovarian cancer patients led to cost savings. MATERIAL ANDMETHODS:
Secondary objective of a prospective randomised trial of patients with suspected or diagnosed advanced ovarian cancer allocated to conventional or ERAS perioperative management, carried out at a referral centre from June 2014 to March 2018. Treatment was determined by a computer-generated random allocation system.METHODS:
Gross counting was employed to estimate the cost of hospitalisation in wards, intensive care unit (ICU) and surgical care, while micro-costing was used to obtain image and laboratory test costs. Mean costs between trial arms were considered. Sensitivity analyses were performed.RESULTS:
Ninety-nine patients (n = 50 ERAS group, n = 49 Conventional group) were included. Mean costs per patient were 10,719 in the ERAS group and 11,028 in the conventional group, leading to an average saving of 309 per patient. These results were based on 96 patients, excluding 3 extreme outliers mainly related with very high ICU costs. Savings, which were significant for hospital ward costs (-33% total; 759 per patient in first hospitalisation, and 914 per partient/day of readmission) were found as robust in the sensitivity analysis.CONCLUSIONS:
Implementation of an ERAS pathway leads to cost savings when compared to conventional management after AOC surgery.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Neoplasias Ovarianas
/
Recuperação Pós-Cirúrgica Melhorada
Tipo de estudo:
Clinical_trials
/
Health_economic_evaluation
Limite:
Female
/
Humans
Idioma:
En
Revista:
Eur J Surg Oncol
Assunto da revista:
NEOPLASIAS
Ano de publicação:
2022
Tipo de documento:
Article
País de afiliação:
Espanha