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Sleep disorder as a clinical risk factor of major depression: associated with cognitive impairment.
Chen, Ru Feng; Cai, Yuan; Zhu, Zhen Hua; Hou, Wen Long; Chen, Peng; Wang, Jing; Jia, Yi Ming; Zhu, Zheng Bao; Zhang, Yong Hong; Tao, Lu Yang; Wu, Jia Wei; Zhang, Jianping; Zhang, Huiping; Wang, Zhi Xin; Jia, Qiu Fang; Hui, Li.
Afiliação
  • Chen RF; Research Center of Biological Psychiatry, Suzhou Guangji Hospital, School of Basic Medicine and Biological Sciences, Suzhou Medical College of Soochow University, Suzhou 215137, Jiangsu Province, PR China.
  • Cai Y; Research Center of Biological Psychiatry, Suzhou Guangji Hospital, School of Basic Medicine and Biological Sciences, Suzhou Medical College of Soochow University, Suzhou 215137, Jiangsu Province, PR China.
  • Zhu ZH; Research Center of Biological Psychiatry, Suzhou Guangji Hospital, School of Basic Medicine and Biological Sciences, Suzhou Medical College of Soochow University, Suzhou 215137, Jiangsu Province, PR China.
  • Hou WL; Research Center of Biological Psychiatry, Suzhou Guangji Hospital, School of Basic Medicine and Biological Sciences, Suzhou Medical College of Soochow University, Suzhou 215137, Jiangsu Province, PR China.
  • Chen P; Research Center of Biological Psychiatry, Suzhou Guangji Hospital, School of Basic Medicine and Biological Sciences, Suzhou Medical College of Soochow University, Suzhou 215137, Jiangsu Province, PR China.
  • Wang J; Research Center of Biological Psychiatry, Suzhou Guangji Hospital, School of Basic Medicine and Biological Sciences, Suzhou Medical College of Soochow University, Suzhou 215137, Jiangsu Province, PR China.
  • Jia YM; Department of Epidemiology, School of Public Health and Jiangsu Key Laboratory of Preventive and Translational Medicine for Geriatric Diseases, Suzhou Medical College of Soochow University, Suzhou 215123, Jiangsu Province, PR China.
  • Zhu ZB; Department of Epidemiology, School of Public Health and Jiangsu Key Laboratory of Preventive and Translational Medicine for Geriatric Diseases, Suzhou Medical College of Soochow University, Suzhou 215123, Jiangsu Province, PR China.
  • Zhang YH; Department of Epidemiology, School of Public Health and Jiangsu Key Laboratory of Preventive and Translational Medicine for Geriatric Diseases, Suzhou Medical College of Soochow University, Suzhou 215123, Jiangsu Province, PR China.
  • Tao LY; Research Center of Biological Psychiatry, Suzhou Guangji Hospital, School of Basic Medicine and Biological Sciences, Suzhou Medical College of Soochow University, Suzhou 215137, Jiangsu Province, PR China.
  • Wu JW; Research Center of Biological Psychiatry, Suzhou Guangji Hospital, School of Basic Medicine and Biological Sciences, Suzhou Medical College of Soochow University, Suzhou 215137, Jiangsu Province, PR China.
  • Zhang J; Department of Psychiatry, Weill Cornell Medical College, Cornell University, New York, NY 10605, USA.
  • Zhang H; Departments of Psychiatry and Medicine (Biomedical Genetics), Boston University School of Medicine, Boston, MA 02118-2526, USA.
  • Wang ZX; Research Center of Biological Psychiatry, Suzhou Guangji Hospital, School of Basic Medicine and Biological Sciences, Suzhou Medical College of Soochow University, Suzhou 215137, Jiangsu Province, PR China. Electronic address: zhixinwang@suda.edu.cn.
  • Jia QF; Research Center of Biological Psychiatry, Suzhou Guangji Hospital, School of Basic Medicine and Biological Sciences, Suzhou Medical College of Soochow University, Suzhou 215137, Jiangsu Province, PR China. Electronic address: 15774374554@qq.com.
  • Hui L; Research Center of Biological Psychiatry, Suzhou Guangji Hospital, School of Basic Medicine and Biological Sciences, Suzhou Medical College of Soochow University, Suzhou 215137, Jiangsu Province, PR China. Electronic address: huili004100@126.com.
Asian J Psychiatr ; 76: 103228, 2022 Oct.
Article em En | MEDLINE | ID: mdl-35973338
BACKGROUND: This research aims explored the sleep disorder (SD) role in major depressive disorder (MDD), and the SD influencing their cognition. METHODS: 372 MDD patients and 457 healthy controls (HCs) were enrolled. RESULTS: Patients increased a 38.88 times SD risk compared with HCs. In patients, visuospatial/constructional score was lower in SD than non-SD, and PSQI score was negatively associated with visuospatial/constructional score of SD. In SD and non-SD, RBANS scores were lower in MDD than HCs, excepted for visuospatial/constructional in non-SD. CONCLUSION: The SD as a MDD risk factor, has more serious visuospatial/constructional impairment alleviated via improving sleep/depression in patients.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Transtornos do Sono-Vigília / Transtorno Depressivo Maior / Disfunção Cognitiva Tipo de estudo: Etiology_studies / Risk_factors_studies Limite: Humans Idioma: En Revista: Asian J Psychiatr Ano de publicação: 2022 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Transtornos do Sono-Vigília / Transtorno Depressivo Maior / Disfunção Cognitiva Tipo de estudo: Etiology_studies / Risk_factors_studies Limite: Humans Idioma: En Revista: Asian J Psychiatr Ano de publicação: 2022 Tipo de documento: Article