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JM-20, a Benzodiazepine-Dihydropyridine Hybrid Molecule, Inhibits the Formation of Alpha-Synuclein-Aggregated Species.
Santos, Cleonice Creusa; Cardim-Pires, Thyago R; Shvachiy, Liana; Fonseca-Fonseca, Luis Arturo; Muñoz, Patricia; Almeida, Áurea Maria A N; Costa, Ana Carla S; Teles-Souza, Jéssica; Ochoa-Rodríguez, Estael; de Fátima Dias Costa, Maria; Palhano, Fernando L; Segura-Aguilar, Juan; Barbosa, Deyse B; do Bomfim, Mayra R; Dos Santos Junior, Manoelito C; Leite, Franco Henrique A; da Rocha Pita, Samuel Silva; Costa, Silvia Lima; Núñez-Figueredo, Yanier; Outeiro, Tiago Fleming; Foguel, Débora; Silva, Victor Diogenes Amaral.
Afiliação
  • Santos CC; Laboratory of Neurochemistry and Cell Biology, Department of Biochemistry and Biophysics, Federal University of Bahia - Institute of Health Sciences, Salvador, 40110-100, Brazil.
  • Cardim-Pires TR; Institute of Medical Biochemistry Leopoldo de Meis, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.
  • Shvachiy L; Department of Experimental Neurodegeneration, Center for Biostructural Imaging of Neurodegeneration, University Medical Center Gottingen, Göttingen, Germany.
  • Fonseca-Fonseca LA; Faculdade de Medicina, Centro Cardiovascular da Universidade de Lisboa, Universidade de Lisboa, Av Prof Egas Moniz, 1649-028, Lisbon, Portugal.
  • Muñoz P; Centro de Investigación y Desarrollo de Medicamentos (CIDEM), La Habana, Cuba.
  • Almeida ÁMAN; Instituto de Ciencias Biomedicas, Facultad de Ciencias de la Salud, Universidad Autónoma de Chile, Santiago, Chile.
  • Costa ACS; Laboratory of Neurochemistry and Cell Biology, Department of Biochemistry and Biophysics, Federal University of Bahia - Institute of Health Sciences, Salvador, 40110-100, Brazil.
  • Teles-Souza J; Laboratory of Neurochemistry and Cell Biology, Department of Biochemistry and Biophysics, Federal University of Bahia - Institute of Health Sciences, Salvador, 40110-100, Brazil.
  • Ochoa-Rodríguez E; Laboratory of Neurochemistry and Cell Biology, Department of Biochemistry and Biophysics, Federal University of Bahia - Institute of Health Sciences, Salvador, 40110-100, Brazil.
  • de Fátima Dias Costa M; Organic Synthesis Laboratory of the Faculty of Chemistry of the University of Havana, Havana, Cuba.
  • Palhano FL; Laboratory of Neurochemistry and Cell Biology, Department of Biochemistry and Biophysics, Federal University of Bahia - Institute of Health Sciences, Salvador, 40110-100, Brazil.
  • Segura-Aguilar J; Institute of Medical Biochemistry Leopoldo de Meis, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.
  • Barbosa DB; Molecular & Clinical Pharmacology, Faculty of Medicine, ICBM, University of Chile, Santiago, Chile.
  • do Bomfim MR; Laboratory of Molecular Modeling, Department of Health, State University of Feira de Santana, Feira de Santana, Brazil.
  • Dos Santos Junior MC; Laboratory of Molecular Modeling, Department of Health, State University of Feira de Santana, Feira de Santana, Brazil.
  • Leite FHA; Laboratory of Molecular Modeling, Department of Health, State University of Feira de Santana, Feira de Santana, Brazil.
  • da Rocha Pita SS; Laboratory of Molecular Modeling, Department of Health, State University of Feira de Santana, Feira de Santana, Brazil.
  • Costa SL; Bioinformatics and Molecular Modeling Laboratory (LaBiMM), Federal University of Bahia - College of Pharmacy, Salvador, Brazil.
  • Núñez-Figueredo Y; Laboratory of Neurochemistry and Cell Biology, Department of Biochemistry and Biophysics, Federal University of Bahia - Institute of Health Sciences, Salvador, 40110-100, Brazil.
  • Outeiro TF; Centro de Investigación y Desarrollo de Medicamentos (CIDEM), La Habana, Cuba.
  • Foguel D; Department of Experimental Neurodegeneration, Center for Biostructural Imaging of Neurodegeneration, University Medical Center Gottingen, Göttingen, Germany.
  • Silva VDA; Max Planck Institute for Multidisciplinary Sciences, Goettingen, Germany.
Neurotox Res ; 40(6): 2135-2147, 2022 Dec.
Article em En | MEDLINE | ID: mdl-35997936
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doença de Parkinson / Di-Hidropiridinas / Neuroblastoma Limite: Humans Idioma: En Revista: Neurotox Res Assunto da revista: NEUROLOGIA Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Brasil
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doença de Parkinson / Di-Hidropiridinas / Neuroblastoma Limite: Humans Idioma: En Revista: Neurotox Res Assunto da revista: NEUROLOGIA Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Brasil