A spatially resolved stochastic model reveals the role of supercoiling in transcription regulation.

Geng, Yuncong; Bohrer, Christopher Herrick; Yehya, Nicolás; Hendrix, Hunter; Shachaf, Lior; Liu, Jian; Xiao, Jie; Roberts, Elijah

Geng, Yuncong; Bohrer, Christopher Herrick; Yehya, Nicolás; Hendrix, Hunter; Shachaf, Lior; Liu, Jian; Xiao, Jie; Roberts, Elijah.

Afiliação

Geng Y; Department of Biomedical Engineering, Johns Hopkins School of Medicine, Baltimore, Maryland, United States of America.
Bohrer CH; Department of Biophysics, Johns Hopkins University, Baltimore, Maryland, United States of America.
Yehya N; Department of Biophysics and Biophysical Chemistry, Johns Hopkins School of Medicine, Baltimore, Maryland, United States of America.
Hendrix H; Department of Biophysics and Biophysical Chemistry, Johns Hopkins School of Medicine, Baltimore, Maryland, United States of America.
Shachaf L; Department of Biophysics and Biophysical Chemistry, Johns Hopkins School of Medicine, Baltimore, Maryland, United States of America.
Liu J; Department of Biophysics, Johns Hopkins University, Baltimore, Maryland, United States of America.
Xiao J; Center for Cell Dynamics, Department of Cell Biology, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America.
Roberts E; Department of Biophysics and Biophysical Chemistry, Johns Hopkins School of Medicine, Baltimore, Maryland, United States of America.

PLoS Comput Biol ; 18(9): e1009788, 2022 09.

Article em En | MEDLINE | ID: mdl-36121892

Assuntos

RNA Polimerases Dirigidas por DNA; Transcrição Gênica; RNA Polimerases Dirigidas por DNA/metabolismo; Escherichia coli/genética; Escherichia coli/metabolismo; Regulação Bacteriana da Expressão Gênica/genética; Transcrição Gênica/genética

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Transcrição Gênica / RNA Polimerases Dirigidas por DNA Tipo de estudo: Prognostic_studies Idioma: En Revista: PLoS Comput Biol Assunto da revista: BIOLOGIA / INFORMATICA MEDICA Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Estados Unidos

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