Histidine supplementation can escalate or rescue HARS deficiency in a Charcot-Marie-Tooth disease model.

Qiu, Yi; Kenana, Rosan; Beharry, Aruun; Wilhelm, Sarah D P; Hsu, Sung Yuan; Siu, Victoria M; Duennwald, Martin; Heinemann, Ilka U

Qiu, Yi; Kenana, Rosan; Beharry, Aruun; Wilhelm, Sarah D P; Hsu, Sung Yuan; Siu, Victoria M; Duennwald, Martin; Heinemann, Ilka U.

Afiliação

Qiu Y; Department of Biochemistry, The University of Western Ontario, London, ON N6A 5C1, Canada.
Kenana R; Department of Biochemistry, The University of Western Ontario, London, ON N6A 5C1, Canada.
Beharry A; Department of Biochemistry, The University of Western Ontario, London, ON N6A 5C1, Canada.
Wilhelm SDP; Department of Biochemistry, The University of Western Ontario, London, ON N6A 5C1, Canada.
Hsu SY; Department of Biochemistry, The University of Western Ontario, London, ON N6A 5C1, Canada.
Siu VM; Department of Biochemistry, The University of Western Ontario, London, ON N6A 5C1, Canada.
Duennwald M; Department of Anatomy and Cell Biology, The University of Western Ontario, London, ON N6A 5C1, Canada.
Heinemann IU; Department of Biochemistry, The University of Western Ontario, London, ON N6A 5C1, Canada.

Hum Mol Genet ; 32(5): 810-824, 2023 02 19.

Article em En | MEDLINE | ID: mdl-36164730

Assuntos

Aminoacil-tRNA Sintetases; Doença de Charcot-Marie-Tooth; Humanos; Doença de Charcot-Marie-Tooth/genética; Histidina/genética; Saccharomyces cerevisiae/genética; Aminoacil-tRNA Sintetases/genética; Mutação; RNA de Transferência/genética; Suplementos Nutricionais

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doença de Charcot-Marie-Tooth / Aminoacil-tRNA Sintetases Limite: Humans Idioma: En Revista: Hum Mol Genet Assunto da revista: BIOLOGIA MOLECULAR / GENETICA MEDICA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Canadá

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