Bariatric surgery prevents carotid wall thickness progression.
Wien Klin Wochenschr
; 135(5-6): 151-157, 2023 Mar.
Article
em En
| MEDLINE
| ID: mdl-36205799
ABSTRACT
BACKGROUND:
Bariatric surgery is a treatment option for patients with severe obesity and improves parameters of cardiovascular and/or metabolic disease. Carotid intima media thickness (C-IMT) is a surrogate measure of subclinical atherosclerosis. Previous studies showed short to mid-term arrest and even regression of CIMT progression following bariatric surgery. We aimed to investigate the long-term effect of weight loss on CIMT progression 10 years after bariatric surgery in comparison to a population-based control cohort.METHODS:
In total, 21 eligible patients were examined preoperatively, at 5 and 10 years after bariatric surgery. Anthropometric parameters, plasma triglycerides, total cholesterol, high-density lipoprotein cholesterol (HDL-C), insulin, and glucose were assessed at all three study visits. CIMT was measured via Bmode scans of the common carotid artery. CIMT progression was measured in an age-matched and BMI-matched cohort selected from the population-based Bruneck study to compare with changes in CIMT progression after bariatric surgery.RESULTS:
CIMT remained stable over the 10-year observation period after bariatric surgery. The control cohort showed a significant CIMT progression over 10 years. The difference in CIMT progression over 10 years was significant (pâ¯< 0.01) between both cohorts.CONCLUSION:
Weight loss induced by bariatric surgery halts the natural progression of CIMT over a 10-year observation period.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Doenças das Artérias Carótidas
/
Aterosclerose
/
Cirurgia Bariátrica
/
Espessura Intima-Media Carotídea
Limite:
Adult
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
Wien Klin Wochenschr
Ano de publicação:
2023
Tipo de documento:
Article
País de afiliação:
Áustria