Epigenomic and transcriptomic landscaping unraveled candidate repositioned therapeutics for non-functioning pituitary neuroendocrine tumors.

Aydin, B; Beklen, H; Arga, K Y; Bayrakli, F; Turanli, B

Aydin, B; Beklen, H; Arga, K Y; Bayrakli, F; Turanli, B.

Afiliação

Aydin B; Department of Bioengineering, Faculty of Engineering and Architecture, Konya Food and Agriculture University, Konya, Turkey.
Beklen H; Department of Bioengineering, Faculty of Engineering, Marmara University, RTE Basibuyuk Campus, 34720, Istanbul, Turkey.
Arga KY; Department of Bioengineering, Faculty of Engineering, Marmara University, RTE Basibuyuk Campus, 34720, Istanbul, Turkey.
Bayrakli F; Genetic and Metabolic Diseases Research and Investigation Center (GEMHAM), Marmara University, Istanbul, Turkey.
Turanli B; Department of Neurosurgery, Faculty of Medicine, Marmara University, Istanbul, Turkey.

J Endocrinol Invest ; 46(4): 727-747, 2023 Apr.

Article em En | MEDLINE | ID: mdl-36306107

Assuntos

Tumores Neuroendócrinos; Neoplasias Hipofisárias; Humanos; Transcriptoma; Tumores Neuroendócrinos/tratamento farmacológico; Tumores Neuroendócrinos/genética; Tumores Neuroendócrinos/diagnóstico; Simulação de Acoplamento Molecular; Epigenômica; Neoplasias Hipofisárias/tratamento farmacológico; Neoplasias Hipofisárias/genética; Neoplasias Hipofisárias/diagnóstico; Proteínas de Grupo de Alta Mobilidade/genética; Proteínas Repressoras

Palavras-chave

DNA methylation; Drug repositioning; Non-coding RNAs; Non-functioning pituitary adenoma; Non-functioning pituitary neuroendocrine tumor (NF-PitNET); Repositioned therapeutics

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Hipofisárias / Tumores Neuroendócrinos Tipo de estudo: Clinical_trials Limite: Humans Idioma: En Revista: J Endocrinol Invest Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Turquia

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