To incise or not and where: SET-domain methyltransferases know.

Yancoskie, Michelle N; Maritz, Corina; van Eijk, Patrick; Reed, Simon H; Naegeli, Hanspeter

Yancoskie, Michelle N; Maritz, Corina; van Eijk, Patrick; Reed, Simon H; Naegeli, Hanspeter.

Afiliação

Yancoskie MN; Institute of Pharmacology and Toxicology, University of Zurich-Vetsuisse, Zurich, Switzerland.
Maritz C; Institute of Pharmacology and Toxicology, University of Zurich-Vetsuisse, Zurich, Switzerland.
van Eijk P; Institute of Cancer and Genetics, School of Medicine, Cardiff University, Cardiff, UK.
Reed SH; Institute of Cancer and Genetics, School of Medicine, Cardiff University, Cardiff, UK.
Naegeli H; Institute of Pharmacology and Toxicology, University of Zurich-Vetsuisse, Zurich, Switzerland. Electronic address: hanspeter.naegeli@uzh.ch.

Trends Biochem Sci ; 48(4): 321-330, 2023 04.

Article em En | MEDLINE | ID: mdl-36357311

Assuntos

Cromatina; Metiltransferases; Metiltransferases/metabolismo; Metilação; Proteínas de Ligação a DNA/metabolismo; Regulação da Expressão Gênica

Palavras-chave

DNA bulky lesion; DNA cleavage; DNA double-strand break; H3K4me3; chromatin; nuclease; topologically associating domain (TAD)

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Cromatina / Metiltransferases Idioma: En Revista: Trends Biochem Sci Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Suíça

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