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Intranasally administered human MSC-derived extracellular vesicles inhibit NLRP3-p38/MAPK signaling after TBI and prevent chronic brain dysfunction.
Kodali, Maheedhar; Madhu, Leelavathi N; Reger, Roxanne L; Milutinovic, Bojana; Upadhya, Raghavendra; Gonzalez, Jenny J; Attaluri, Sahithi; Shuai, Bing; Gitai, Daniel L G; Rao, Shama; Choi, Jong M; Jung, Sung Y; Shetty, Ashok K.
Afiliação
  • Kodali M; Institute for Regenerative Medicine, Department of Cell Biology and Genetics, Texas A&M University School of Medicine, College Station, TX, USA.
  • Madhu LN; Institute for Regenerative Medicine, Department of Cell Biology and Genetics, Texas A&M University School of Medicine, College Station, TX, USA.
  • Reger RL; Institute for Regenerative Medicine, Department of Cell Biology and Genetics, Texas A&M University School of Medicine, College Station, TX, USA.
  • Milutinovic B; Institute for Regenerative Medicine, Department of Cell Biology and Genetics, Texas A&M University School of Medicine, College Station, TX, USA.
  • Upadhya R; Institute for Regenerative Medicine, Department of Cell Biology and Genetics, Texas A&M University School of Medicine, College Station, TX, USA.
  • Gonzalez JJ; Institute for Regenerative Medicine, Department of Cell Biology and Genetics, Texas A&M University School of Medicine, College Station, TX, USA.
  • Attaluri S; Institute for Regenerative Medicine, Department of Cell Biology and Genetics, Texas A&M University School of Medicine, College Station, TX, USA.
  • Shuai B; Institute for Regenerative Medicine, Department of Cell Biology and Genetics, Texas A&M University School of Medicine, College Station, TX, USA.
  • Gitai DLG; Institute of Biological Sciences and Health, Federal University of Alagoas, Brazil.
  • Rao S; Institute for Regenerative Medicine, Department of Cell Biology and Genetics, Texas A&M University School of Medicine, College Station, TX, USA.
  • Choi JM; Advanced Technology Core, Mass Spectrometry and Proteomics Core, Baylor College of Medicine, Houston, TX, USA.
  • Jung SY; The Verna and Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, TX, USA.
  • Shetty AK; Institute for Regenerative Medicine, Department of Cell Biology and Genetics, Texas A&M University School of Medicine, College Station, TX, USA. Electronic address: ash.shetty@tamu.edu.
Brain Behav Immun ; 108: 118-134, 2023 Feb.
Article em En | MEDLINE | ID: mdl-36427808
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: MicroRNAs / Proteína Quinase 14 Ativada por Mitógeno / Vesículas Extracelulares / Lesões Encefálicas Traumáticas Limite: Animals / Humans Idioma: En Revista: Brain Behav Immun Assunto da revista: ALERGIA E IMUNOLOGIA / CEREBRO / PSICOFISIOLOGIA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Estados Unidos
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: MicroRNAs / Proteína Quinase 14 Ativada por Mitógeno / Vesículas Extracelulares / Lesões Encefálicas Traumáticas Limite: Animals / Humans Idioma: En Revista: Brain Behav Immun Assunto da revista: ALERGIA E IMUNOLOGIA / CEREBRO / PSICOFISIOLOGIA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Estados Unidos