Design, synthesis of 1,2,4-triazine derivatives as antidepressant and antioxidant agents: In vitro, in vivo and in silico studies.

Pal, Rohit; Kumar, Bhupinder; Swamy P M, Guruubasavaraja; Chawla, Pooja A

Pal, Rohit; Kumar, Bhupinder; Swamy P M, Guruubasavaraja; Chawla, Pooja A.

Afiliação

Pal R; Department of Pharmaceutical Chemistry, ISF College of Pharmacy, GT Road, Ghal Kalan, Moga-142001, Punjab, India; Department of Pharmaceutical Chemistry, Acharya & BM Reddy College of Pharmacy, Bengaluru 560107, Karnataka, India.
Kumar B; Department of Pharmaceutical Chemistry, ISF College of Pharmacy, GT Road, Ghal Kalan, Moga-142001, Punjab, India.
Swamy P M G; Department of Pharmaceutical Chemistry, Acharya & BM Reddy College of Pharmacy, Bengaluru 560107, Karnataka, India.
Chawla PA; Department of Pharmaceutical Chemistry, ISF College of Pharmacy, GT Road, Ghal Kalan, Moga-142001, Punjab, India. Electronic address: pvchawla@gmail.com.

Bioorg Chem ; 131: 106284, 2023 02.

Article em En | MEDLINE | ID: mdl-36444791

Assuntos

Antioxidantes; Natação; Antioxidantes/farmacologia; Antidepressivos/farmacologia; Antidepressivos/química; Triazinas/farmacologia; Benzamidas

Palavras-chave

Actophotometer; Antidepressant; Forced swimming test; MAO-A; Tail suspension test; Triazine

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Natação / Antioxidantes Tipo de estudo: Prognostic_studies Idioma: En Revista: Bioorg Chem Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Índia

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