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Developing Artificial Intelligence Models for Extracting Oncologic Outcomes from Japanese Electronic Health Records.
Araki, Kenji; Matsumoto, Nobuhiro; Togo, Kanae; Yonemoto, Naohiro; Ohki, Emiko; Xu, Linghua; Hasegawa, Yoshiyuki; Satoh, Daisuke; Takemoto, Ryota; Miyazaki, Taiga.
Afiliação
  • Araki K; Patient Advocacy Center, University of Miyazaki Hospital, Miyazaki, Japan.
  • Matsumoto N; Division of Respirology, Rheumatology, Infectious Diseases, and Neurology, Department of Internal Medicine, University of Miyazaki, Miyazaki, Japan.
  • Togo K; Health & Value, Pfizer Japan Inc., Tokyo, Japan. kanae.togo@pfizer.com.
  • Yonemoto N; Health & Value, Pfizer Japan Inc., Tokyo, Japan.
  • Ohki E; Oncology Medical Affairs, Pfizer Japan Inc, Tokyo, Japan.
  • Xu L; Health & Value, Pfizer Japan Inc., Tokyo, Japan.
  • Hasegawa Y; Manufacturing IT Innovation Sector, NTT DATA Corporation, Tokyo, Japan.
  • Satoh D; Research and Development Headquarters, NTT DATA Corporation, Tokyo, Japan.
  • Takemoto R; Manufacturing IT Innovation Sector, NTT DATA Corporation, Tokyo, Japan.
  • Miyazaki T; Division of Respirology, Rheumatology, Infectious Diseases, and Neurology, Department of Internal Medicine, University of Miyazaki, Miyazaki, Japan.
Adv Ther ; 40(3): 934-950, 2023 03.
Article em En | MEDLINE | ID: mdl-36547809
The use of artificial intelligence (AI) to derive health outcomes from large electronic health records is not well established. Thus, we built three different AI models: Bidirectional Encoder Representations from Transformers (BERT), Naïve Bayes, and Longformer to serve this purpose. Initially, we developed these models based on data from the University of Miyazaki Hospital (UMH) and later improved them using the Life Data Initiative (LDI) data set of six hospitals. The performance of the BERT model was better than the other two, and it showed similar results when it was applied to the LDI data set. The Kaplan­Meier plots of time to progression of disease for the predicted data by the BERT model showed similar trends to those for the manually curated data. In summary, we developed an AI model to extract health outcomes using a large electronic health database in this study; however, the performance of the AI model could be improved using more training data.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Inteligência Artificial / Neoplasias Pulmonares Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Humans Idioma: En Revista: Adv Ther Assunto da revista: TERAPEUTICA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Japão

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Inteligência Artificial / Neoplasias Pulmonares Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Humans Idioma: En Revista: Adv Ther Assunto da revista: TERAPEUTICA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Japão