Mechanism of IFT-A polymerization into trains for ciliary transport.

Meleppattu, Shimi; Zhou, Haixia; Dai, Jin; Gui, Miao; Brown, Alan

Meleppattu, Shimi; Zhou, Haixia; Dai, Jin; Gui, Miao; Brown, Alan.

Afiliação

Meleppattu S; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, 240 Longwood Avenue, Boston, MA 02115, USA.
Zhou H; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, 240 Longwood Avenue, Boston, MA 02115, USA.
Dai J; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, 240 Longwood Avenue, Boston, MA 02115, USA.
Gui M; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, 240 Longwood Avenue, Boston, MA 02115, USA.
Brown A; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, 240 Longwood Avenue, Boston, MA 02115, USA. Electronic address: alan_brown@hms.harvard.edu.

Cell ; 185(26): 4986-4998.e12, 2022 12 22.

Article em En | MEDLINE | ID: mdl-36563665

Assuntos

Cílios; Proteínas; Polimerização; Transporte Biológico; Cílios/metabolismo; Proteínas/metabolismo; Microtúbulos/metabolismo; Flagelos/metabolismo; Transporte Proteico

Palavras-chave

cilia; cryo-EM; cryo-ET; flagella; intraflagellar transport; lipid binding; microtubule; molecular transport; vesicle

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas / Cílios Idioma: En Revista: Cell Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Estados Unidos

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