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CRISPR/Cas9-mediated inactivation of the phosphatase activity of soluble epoxide hydrolase prevents obesity and cardiac ischemic injury.
Leuillier, Matthieu; Duflot, Thomas; Ménoret, Séverine; Messaoudi, Hind; Djerada, Zoubir; Groussard, Déborah; Denis, Raphaël G P; Chevalier, Laurence; Karoui, Ahmed; Panthu, Baptiste; Thiébaut, Pierre-Alain; Schmitz-Afonso, Isabelle; Nobis, Séverine; Campart, Cynthia; Henry, Tiphaine; Sautreuil, Camille; Luquet, Serge H; Beseme, Olivia; Féliu, Catherine; Peyret, Hélène; Nicol, Lionel; Henry, Jean-Paul; Renet, Sylvanie; Mulder, Paul; Wan, Debin; Tesson, Laurent; Heslan, Jean-Marie; Duché, Angéline; Jacques, Sébastien; Ziegler, Frédéric; Brunel, Valéry; Rautureau, Gilles J P; Monteil, Christelle; do Rego, Jean-Luc; do Rego, Jean-Claude; Afonso, Carlos; Hammock, Bruce; Madec, Anne-Marie; Pinet, Florence; Richard, Vincent; Anegon, Ignacio; Guignabert, Christophe; Morisseau, Christophe; Bellien, Jérémy.
Afiliação
  • Leuillier M; Normandy University, UniRouen, Inserm UMR1096 EnVI, FHU REMOD-VHF, F-76000 Rouen, France.
  • Duflot T; Normandy University, UniRouen, Inserm UMR1096 EnVI, FHU REMOD-VHF, F-76000 Rouen, France; Department of Pharmacology, Rouen University Hospital, F-76000 Rouen, France; Laboratory of Pharmacokinetics, Toxicology and Pharmacogenetics, Rouen University Hospital, F-76000 Rouen, France.
  • Ménoret S; Nantes Université, CHU Nantes, Inserm, CNRS, SFR Santé, Inserm UMS 016, CNRS UMS 3556, F-44000 Nantes, France; Nantes Université, CHU Nantes, Inserm, Centre de Recherche en Transplantation et Immunologie, UMR 1064, ITUN, F-44000 Nantes, France; Transgenesis Rat ImmunoPhenomic Platform, F-44000 Nante
  • Messaoudi H; Normandy University, UniRouen, Inserm UMR1096 EnVI, FHU REMOD-VHF, F-76000 Rouen, France.
  • Djerada Z; Department of Pharmacology, EA 3801, SFR CAP-santé, Reims University Hospital, F-51095 Reims Cedex, France.
  • Groussard D; Normandy University, UniRouen, Inserm UMR1096 EnVI, FHU REMOD-VHF, F-76000 Rouen, France.
  • Denis RGP; Unité de Biologie Fonctionnelle et Adaptative, Centre National la Recherche scientifique, Université de Paris, BFA, UMR 8251, CNRS, F-75013 Paris, France.
  • Chevalier L; Normandie University, Unirouen, INSA Rouen, CNRS, Groupe de Physique des Matériaux-UMR6634, F-76000 Rouen, France.
  • Karoui A; Normandie Univ, UNIROUEN, UNICAEN, ABTE, F-76000 Rouen, France.
  • Panthu B; CarMeN Laboratory, INSERM, INRA, INSA, Université Claude Bernard Lyon 1, F-69600 Oullins, France.
  • Thiébaut PA; Pathology Department, Rouen University Hospital, F-76000 Rouen, France.
  • Schmitz-Afonso I; Normandie Univ, COBRA, UMR 6014 and FR 3038, Université de Rouen, INSA de Rouen, CNRS, IRCOF, F-76821, Mont-Saint-Aignan, Cedex, France.
  • Nobis S; Animal Behavioral Platform (SCAC), HeRacLeS Inserm US51-CNRS UAR2026, Institute for Research and Innovation in Biomedicine (IRIB), University of Rouen Normandy, F-76183 Rouen, France.
  • Campart C; Animal Behavioral Platform (SCAC), HeRacLeS Inserm US51-CNRS UAR2026, Institute for Research and Innovation in Biomedicine (IRIB), University of Rouen Normandy, F-76183 Rouen, France.
  • Henry T; Animal Behavioral Platform (SCAC), HeRacLeS Inserm US51-CNRS UAR2026, Institute for Research and Innovation in Biomedicine (IRIB), University of Rouen Normandy, F-76183 Rouen, France.
  • Sautreuil C; Normandie Univ, UNIROUEN, INSERM U1245 and Rouen University Hospital, Department of Neonatal Paediatrics and Intensive Care, F-76000, Normandy Centre for Genomic and Personalized Medicine, Rouen, France.
  • Luquet SH; Unité de Biologie Fonctionnelle et Adaptative, Centre National la Recherche scientifique, Université de Paris, BFA, UMR 8251, CNRS, F-75013 Paris, France.
  • Beseme O; Univ. Lille, CHU Lille, Inserm, Institut Pasteur de Lille, U1167 - RID-AGE - Facteurs de risque et déterminants moléculaires des maladies liées au vieillissement, F-59000 Lille, France.
  • Féliu C; Department of Pharmacology, EA 3801, SFR CAP-santé, Reims University Hospital, F-51095 Reims Cedex, France.
  • Peyret H; Department of Pharmacology, EA 3801, SFR CAP-santé, Reims University Hospital, F-51095 Reims Cedex, France.
  • Nicol L; Normandy University, UniRouen, Inserm UMR1096 EnVI, FHU REMOD-VHF, F-76000 Rouen, France.
  • Henry JP; Normandy University, UniRouen, Inserm UMR1096 EnVI, FHU REMOD-VHF, F-76000 Rouen, France.
  • Renet S; Normandy University, UniRouen, Inserm UMR1096 EnVI, FHU REMOD-VHF, F-76000 Rouen, France.
  • Mulder P; Normandy University, UniRouen, Inserm UMR1096 EnVI, FHU REMOD-VHF, F-76000 Rouen, France.
  • Wan D; Department of Entomology and Nematology, and UCD Comprehensive Cancer Center, University of California, Davis, CA 95616, USA.
  • Tesson L; Nantes Université, CHU Nantes, Inserm, CNRS, SFR Santé, Inserm UMS 016, CNRS UMS 3556, F-44000 Nantes, France; Nantes Université, CHU Nantes, Inserm, Centre de Recherche en Transplantation et Immunologie, UMR 1064, ITUN, F-44000 Nantes, France; Transgenesis Rat ImmunoPhenomic Platform, F-44000 Nante
  • Heslan JM; Nantes Université, CHU Nantes, Inserm, CNRS, SFR Santé, Inserm UMS 016, CNRS UMS 3556, F-44000 Nantes, France; Nantes Université, CHU Nantes, Inserm, Centre de Recherche en Transplantation et Immunologie, UMR 1064, ITUN, F-44000 Nantes, France; GenoCellEdit Platform, F-44000 Nantes, France.
  • Duché A; Institut Cochin, U1016 INSERM - UMR8104, CNRS - Université Paris Descartes, Genom'IC Platform, Bâtiment Gustave Roussy, F-75014 Paris, France.
  • Jacques S; Institut Cochin, U1016 INSERM - UMR8104, CNRS - Université Paris Descartes, Genom'IC Platform, Bâtiment Gustave Roussy, F-75014 Paris, France.
  • Ziegler F; Department of General Biochemistry, Rouen University Hospital, 76000 Rouen, France.
  • Brunel V; Department of General Biochemistry, Rouen University Hospital, 76000 Rouen, France.
  • Rautureau GJP; Centre de Résonance Magnétique Nucléaire à Très hauts Champs (FRE 2034, CNRS, Ecole Normale Supérieure de Lyon, Université Claude Bernard Lyon 1), Université de Lyon, F-69100 Villeurbanne, France.
  • Monteil C; Normandie Univ, UNIROUEN, UNICAEN, ABTE, F-76000 Rouen, France.
  • do Rego JL; Animal Behavioral Platform (SCAC), HeRacLeS Inserm US51-CNRS UAR2026, Institute for Research and Innovation in Biomedicine (IRIB), University of Rouen Normandy, F-76183 Rouen, France.
  • do Rego JC; Animal Behavioral Platform (SCAC), HeRacLeS Inserm US51-CNRS UAR2026, Institute for Research and Innovation in Biomedicine (IRIB), University of Rouen Normandy, F-76183 Rouen, France.
  • Afonso C; Normandie Univ, COBRA, UMR 6014 and FR 3038, Université de Rouen, INSA de Rouen, CNRS, IRCOF, F-76821, Mont-Saint-Aignan, Cedex, France.
  • Hammock B; Department of Entomology and Nematology, and UCD Comprehensive Cancer Center, University of California, Davis, CA 95616, USA.
  • Madec AM; CarMeN Laboratory, INSERM, INRA, INSA, Université Claude Bernard Lyon 1, F-69600 Oullins, France.
  • Pinet F; Institut Cochin, U1016 INSERM - UMR8104, CNRS - Université Paris Descartes, Genom'IC Platform, Bâtiment Gustave Roussy, F-75014 Paris, France.
  • Richard V; Normandy University, UniRouen, Inserm UMR1096 EnVI, FHU REMOD-VHF, F-76000 Rouen, France; Department of Pharmacology, Rouen University Hospital, F-76000 Rouen, France.
  • Anegon I; Nantes Université, CHU Nantes, Inserm, CNRS, SFR Santé, Inserm UMS 016, CNRS UMS 3556, F-44000 Nantes, France; Nantes Université, CHU Nantes, Inserm, Centre de Recherche en Transplantation et Immunologie, UMR 1064, ITUN, F-44000 Nantes, France; Transgenesis Rat ImmunoPhenomic Platform, F-44000 Nante
  • Guignabert C; INSERM UMR_S 999, Hôpital Marie Lannelongue, F-92350 Le Plessis-Robinson, France; Faculté de Médecine, Université Paris-Sud, Université Paris-Saclay, F-94270 Le Kremlin-Bicêtre, France.
  • Morisseau C; Department of Entomology and Nematology, and UCD Comprehensive Cancer Center, University of California, Davis, CA 95616, USA.
  • Bellien J; Normandy University, UniRouen, Inserm UMR1096 EnVI, FHU REMOD-VHF, F-76000 Rouen, France; Department of Pharmacology, Rouen University Hospital, F-76000 Rouen, France. Electronic address: jeremy.bellien@chu-rouen.fr.
J Adv Res ; 43: 163-174, 2023 01.
Article em En | MEDLINE | ID: mdl-36585106
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Epóxido Hidrolases / Traumatismos Cardíacos / Obesidade Limite: Animals Idioma: En Revista: J Adv Res Ano de publicação: 2023 Tipo de documento: Article País de afiliação: França
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Epóxido Hidrolases / Traumatismos Cardíacos / Obesidade Limite: Animals Idioma: En Revista: J Adv Res Ano de publicação: 2023 Tipo de documento: Article País de afiliação: França