[Determination of six arsenic species in urine by high-performance liquid chromatography-inductively coupled plasma-mass spectrometr].
Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi
; 40(12): 952-955, 2022 Dec 20.
Article
em Zh
| MEDLINE
| ID: mdl-36646494
ABSTRACT
Objective:
Establishing an analysis method for the detection of six arsenic compounds trivalent arsenic, pentavalent arsenic, methyl arsenic, dimethyl arsenic, arsenical choline and arsenical betaine in urine by high-performance liquid chromatography-inductively coupled plasma-mass spectrometry (HPLC-ICP-MS) and providing a theoretical basis for health assessment of arsenic poisoning patients.Methods:
HPLC-ICP-MS was used to detect six arsenic compounds with the hamilton PRP-X100 column and aqueous ammonium phosphate in a gradient elution as mobile phase.Results:
There was a good linear relationship in the selected range of six arsenic compounds evidenced by a linear correlation coefficient greater than 0.999. The detection limit of 6 arsenic compounds was 0.46~0.57 µg/L, and the minimum quantitative concentration were 1.52~1.91 µg/L. The recovery rates of six arsenic compounds were 96.5%~106.4%, The within-run and between-run relative standard deviation was 2.9%~6.2% and 3.8%~8.7%.Conclusion:
The established method with high accuracy and precision is suitable for detecting arsenic levels in urine of occupational arsenic exposure population.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Arsênio
/
Arsenicais
Limite:
Humans
Idioma:
Zh
Revista:
Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi
Assunto da revista:
MEDICINA OCUPACIONAL
Ano de publicação:
2022
Tipo de documento:
Article
País de afiliação:
China